开始时间: 04/22/2022 持续时间: Unknown
所在平台: CourseraArchive 课程类别: 生物与生命科学 大学或机构: Hebrew University of Jerusalem(耶路撒冷希伯来大学) 授课老师: Yaakov Nahmias |
课程主页: https://www.coursera.org/course/tissue101
课程评论:没有评论
Tissue Engineering is a rapidly expanding field of applied biology and biomedical engineering that aims to create artificial organs for transplantation, basic research, or drug development. A fascinating aspect of the field is the fundamental need to integrate knowledge of organic chemistry, cell biology, genetics, mechanics and transport processes to create functional organs. The process uncovers the fascinating complexity of living tissues, and the joy of creation.
This course will review basic cell culture techniques, structure function relationships, cellular communication, natural and artificial biomaterials, and the basic equations governing cell survival and tissue organization.
Week One: Introduction. definitions, basic principles, structure-function relationships Week Two: Biomaterials. metals, ceramics, polymers (synthetic and natural). Biodegradable materials,
native matrix Week Three: Tissue culture
basics: primary cells vs. cell lines, sterile techniques, plastics, enzymes,
reactors and cryopreservation Week Four: Oxygen transport. diffusion,
Michalies-Menten kinetics, oxygen uptake rates, limits of diffusion Week Five: Principals of self
assembly. cell migration, 3D organization and angiogenesis Week Six: Skin tissue
engineering. introduction, scar vs. regeneration, split skin graft, apligraf Week Seven: Cardiovascular
tissue engineering. introduction, blood vessels structure, vascular grafts Week Eight: Liver tissue
engineering. bioartificial liver (BAL) assist device, shear forces , oxygen
transport, plasma effects Week Nine: Liver tissue
engineering. self-assembled organoids, decelluarized whole livers Week Ten: Stem cells. basic
principles, embryonic stem cells, induced pluripotent stem cells
Step into the world of Tissue Engineering, a rapidly expanding field of applied biology aiming to create artificial organs for transplantation, basic research, or drug development.
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