Drugs and the Brain

开始时间: 04/22/2022 持续时间: Unknown

课程主页: https://www.coursera.org/course/drugsandbrain

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课程详情

What happens in the body when a person smokes a cigarette? After several weeks of smoking? When a person takes antidepressant or antipsychotic medication? A drug for pain or epilepsy? A recreational drug? Neuroscientists are beginning to understand these processes. You’ll learn how drugs enter the brain, how they act on receptors and ion channels, and how “molecular relay races” lead to changes in nerve cells and neural circuits that far outlast the drugs themselves. “Drugs and the Brain” also describes how scientists are gathering the knowledge required for the next steps in preventing or alleviating Parkinson’s, Alzheimer’s, schizophrenia, and drug abuse.

课程大纲

Week 1. Introductory concepts. Drugs, drug receptors, neuroscience. Resting potentials. Equivalent circuits.

Week 2. Drugs open and block ion channels. Dose-response relations. Desensitization. Epilepsy drugs. Drugs activate and block G protein pathways.

Week 3. Drugs block neurotransmitter transporters. Recreational drugs. Nicotine Addiction.

Week 4. Drugs for neurodegenerative diseases.

Week 5. Drugs for psychiatric diseases. Developing new drugs.

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