|
所在平台: Udemy |
课程主页: https://www.udemy.com/course/practice-and-learn-genome-editing/
课程评论：没有评论
**Coursera 基因编辑实践题库课程总结** 本课程是一门独特的、基于多项选择题的学习课程，旨在通过互动问答激发学习者的思考，确保积极参与。课程包含两套各60道题目，并附有答案和详细解析。 **课程内容涵盖：** * **全面介绍基因编辑技术：** 深入讲解 CRISPR/Cas9、锌指核酸酶（Zinc Finger Nuclease, ZFNs）、转录激活因子样效应物核酸酶（TALENs）和巨核酸酶（Meganucleases）等主流技术。 * **理论与应用并重：** 以问答形式覆盖基因编辑的定义、理论、设计、分析和应用等各个方面。 * **关键知识点：** 学习者将能够掌握 CRISPR/Cas9 的历史、PAM 和间隔序列（Spacer sequence）的作用、导向 RNA（guide RNA）、Cas9 的功能、DNA 双链断裂后 NHEJ 或 HDR 修复机制的激活条件，以及脱靶效应的检测和分析。 * **前沿应用启发：** 课程引用同行评审的科学文献，展示基因编辑技术的当前应用，激发学习者对 CRISPR 和其他基因编辑技术潜在应用领域的想象力。 **学习目标：** 通过其独特的教学方法，本课程旨在帮助学习者深刻理解各种基因编辑技术，特别是 CRISPR/Cas9。完成课程后，学习者将能够自信地应对基因编辑领域的面试、考试及学术讨论。 **核心学习方式：** 本书式学习（Practice and Learn）的问答模式，让学习者在实践中学习基因编辑理论，掌握 CRISPR/Cas9、ZFNs、TALENs、Meganucleases 技术。
Practice and Learn Genome editing course is a unique multiple choice based courses designed to engage the reader through questions. This type of learning stimulates the thought process of learner and ensures active participation. This practice test is a set of two tests containing 60 questions each supplemented with answer and explanation. This course is a complete coverage of genome editing technologies like CRISPR/Cas9, Zinc Finger Nuclease, TALENs and Meganucleases and covers definitions, theory, design, analysis and applications aspect of genome editing in form of questions and answers. After taking this practice test you will be able to answer about the history of CRISPR/Cas9, Role of PAM and Spacer sequence, guide RNA, role of cas9, conditions required for activation of NHEJ or HDR repair mechanism in response to double stranded DNA break and detection and analysis of off target analysis. To have real feel of learning and to nknow where genome editing technologies can be applied, current application from peer reviewed scientific article has been also included to stimulate the imagination of learners regarding potential application of CRISPR and other gene editing technologies.Through its unique pedagogy, this course will be able to develop deep understanding of various genome editing technologies especially CRISPR/Cas9 and prepare the learner to face interview, exam or general debate in Genome editing. Let's embark on a journey to understand genome editing through Practice and Learn Genome Editing- Question and Answer based learning of genome editing-CRISPR/Cas9, Zinc Finger Nuclease, TALENs and Meganucleases
