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所在平台: Udemy |
课程主页: https://www.udemy.com/course/organic-chemistry-bonding-and-molecular-structure/
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这门名为“有机化学 - 键合与分子结构”的Coursera课程，专为面临有机化学学习困难的高中生、化学、药学或生物学专业的学生设计。课程由拥有有机化学博士学位、在制药行业拥有8年以上经验以及4年以上化学教学经验的Mohammad Abualrub博士讲授。 课程旨在帮助学生掌握有机化学的基础知识，克服考试障碍，最终成为有机化学的佼佼者。无论学生是否有化学基础，该课程都将循序渐进地讲解所有必要内容。 课程内容涵盖广泛，包括： * **键合与分子结构**: 原子结构、同位素、价电子、有机化学结构理论、分子式与结构式、异构体、化学键、八隅体规则、路易斯结构、形式电荷、共振、轨道杂化（sp3、sp2、sp1）、双键的限制旋转、顺反异构、sigma键与pi键、分子几何（VSEPR模型）。 * **官能团与物理性质**: 碳化合物家族（官能团）、碳氢化合物、极性共价键、官能团、物理性质与分子结构、离子化合物（离子-离子作用力）、有机化合物的溶解性、分子间力（范德华力）。 * **有机反应与机理**: 亲核取代与消除反应、有机卤化物、亲核试剂、离去基团、SN2和SN1反应动力学、过渡态理论、自由能图、影响反应速率的因素（底物结构、亲核试剂浓度与强度、溶剂效应、离去基团性质）、消除反应（E2和E1）、取代与消除反应判别。 * **酸碱理论**: 酸与碱、共价键的均裂与异裂、酸碱反应、碳正离子、碳负离子、亲电试剂与亲核试剂、布朗斯台德-洛里酸碱强度（Ka和pKa）、预测酸碱反应结果、结构与酸度关系、羧酸的酸度、有机反应机理。 * **烷烃与环烷烃**: 烷烃与环烷烃介绍、烷烃构象、物理性质、命名法则（IUPAC）、支链烷烃命名、支链烷基命名、卤代烷、醇、环烷烃、烯烃、炔烃的命名、sigma键、键旋转与构象、丁烷构象分析、环烷烃相对稳定性（环张力）、环己烷构象（椅式与船式）、取代环己烷（轴向与平伏键）、二取代环己烷、顺反异构。 * **立体化学**: 手性分子、立体化学、异构现象（结构异构体与立体异构体）、对映异构体与手性分子、手性测试（对称面）、对映异构体命名（R/S系统）、对映异构体性质（旋光性）、平面偏振光、外消旋体、手性分子合成、多手性中心分子、内消旋化合物、费雪投影式。 * **有机合成**: 官能团转化（此处可能为概括性描述，具体内容需参考课程详述）。 该课程通过大量的例题来加深学生的理解，并提供30天无条件退款保证，确保学习的零风险。学生可以立即报名，开始学习之旅。
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