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所在平台: Udemy |
课程主页: https://www.udemy.com/course/moe-program-in-computer-aided-drug-design-practical-session/
课程评论：没有评论
课程名称：计算机辅助药物设计实操课程（MOE程序） 课程概述： 计算机辅助药物设计规则的应用至关重要。本课程旨在实践药物设计的基础知识，主要使用MOE程序进行药物设计的相关操作。通过实操环节，学员将学习到以下内容：如何使用MOE程序中的重要工具、如何准备配体并形成适合的数据库、如何获取蛋白质并进行准备、如何定义适当的结合位点、如何为对接过程准备系统、对接验证过程及其重要性、配体与靶标复合物的可视化，以及对接结果的数据解读。 课程还将讨论药物修饰的生物等效性规则，以选择合适的配体。此外，我们将探讨蛋白质-蛋白质对接，作为生物信息学的基础内容。学员将了解如何在计算机辅助药物设计中应用生物信息学规则，深入理解配体在蛋白质结构中的结合亲和力，帮助寻找具有更高亲和力的新化合物。希望本课程能够为您提供充分的知识，了解如何准备库和进行对接。欢迎加入我们的课程，进一步了解和实践您在药物设计方面的基础知识。
Application of computer aided drug design rules is very important so I present this course to practice the basics of drug design In this practical sessions we will know how to use MOE program for drug designingWe will know all important tools in MOE programHow to prepare ligands and form suitable databaseHow to get the protein and prepare it How to define the proper binding sitesHow to prepare The system for docking process Docking validation process and why it is important Ligand target complex visualizationDocking results and Data interpretation.In this course we will discuss the Bioisosterism rules for drug modification to choose the proper ligands.Also we will discuss the protein protein docking as a base for bioinformatics that will be discussed also In this course We will know how use the bioinformatic rules in computer aided drug design This course will help you to deeply know the binding affinities of your ligands inside the protein structure. Which helps you to find new compounds of higher affinities. I hope this course be enough for you to know all about the preparation of libraries and docking Join our course to know more and practice your basics
