Metabolism of Macromolecules

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课程主页: https://www.udemy.com/course/metabolism-e/

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课程简介

**课程名称:** 大分子代谢 **课程概述:** 本课程旨在帮助学习者理解什么是新陈代谢,以及人体内碳水化合物、蛋白质和脂质这三种重要生物分子的代谢过程。课程内容由浅入深,适合初学者和中级水平的学习者。 **课程内容(六讲):** 1. **新陈代谢导论:** 介绍新陈代谢的定义及其重要性。 2. **代谢途径的类型:** 讲解合成代谢、分解代谢和两性代谢三种主要的代谢途径。 3. **碳水化合物代谢:** * 以葡萄糖为主要前体,讲解碳水化合物代谢的基础知识。 * 深入探讨葡萄糖在糖原生成(glycogenesis)和戊糖磷酸途径(PPP)中的作用。 * 分步详细讲解糖酵解(glycolysis)这一碳水化合物代谢的关键过程。 4. **蛋白质代谢:** * **第一部分:** 定义蛋白质代谢,讲解氨基酸的分解代谢,重点阐述脱去氨基的过程。 * 详细介绍蛋白质代谢的两个主要过程:转氨作用(Transamination)和脱氨作用(deamination),并对比两者的区别。 * 讲解体内氮的平衡。 * **第二部分:** 讲解氨基酸库(amino acid pool)。 * 详细分步讲解蛋白质代谢的另一个重要过程——尿素循环(Urea Cycle)及其目的。 5. **脂质代谢:** * 介绍脂质代谢的概况。 * 讲解甘油三酯(triglycerides)的合成过程。 * 详细介绍脂质代谢的各个步骤。

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课程详情

This course will help you to understand what metabolism is and how different biological molecules (carbohydrates, proteins and lipids) metabolism that takes place in the human body. In this course, you will be taught everything step by step as I tried to made it easier as possible for beginners or for intermediate level students that are learning or are interested in understand about what metabolism is in biochemistry. This course consists of six lectures:Introduction to Metabolism- definition and importance of metabolism will be explained.Types of Metabolic pathways-There are three types of metabolic pathways that are anabolic, catabolic and amphibolic pathways will be explained.Carbohydrate Metabolism- Glucose which is the general precursor of carbohydrate metabolism will be given a general idea. The role of glucose in glycogenesis and pentose phosphate pathway(PPP) will be explained in depth. The process of glycolysis that is the major step involved in carbohydrate metabolism will be explained step by step.Protein Metabolism will be divided into two parts:(i) In the first part of the lecture that is the Part 1, definition of protein metabolism will be explained. Amino acid catabolism will be explained. How nitrogen is removed from amino acids will be explained in depth. Two major processes that are involved in protein metabolism: Transamination and deamination will be explained step by step. The differences between them will also be explained. How nitrogen is balanced in our body will also be explained.(ii) In the second part of the lecture that is Part 2, amino acid pool will be explained. Another major process in protein metabolism that is the Urea Cycle will be explained step by step in detail. The purpose of urea cycle will also be explained.Lipid Metabolism- general idea of what lipid metabolism will be explained. How triglycerides are made will be explained. Steps of lipid metabolism will be explained in detail.

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