Mystery Of Genes: Complete Genetics Course-Basic to Advanced

所在平台: Udemy

课程主页: https://www.udemy.com/course/lets-unpuzzle-the-mystery-of-genescomplete-genetics-course/

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课程简介

Coursera 上的“基因的奥秘:从基础到高级的完整遗传学课程”是一门全面的遗传学课程,旨在帮助学生深入了解遗传学的各个方面。 课程内容涵盖: * **遗传学基础:** DNA、RNA(包括不同类型)、染色体、染色单体及其在细胞周期不同阶段的数量计算。 * **遗传与变异:** 进化、遗传、变异的概念,以及孟德尔定律(显性定律、分离定律、自由组合定律)。 * **孟德尔定律的偏离:** 不完全显性、共显性、复等位基因(以ABO血型为例)。 * **遗传分析工具:** 宾氏图(Punnett square)的绘制方法。 * **基因的本质与功能:** 基因、遗传因子、遗传密码、摆动假说(wobble hypothesis)、多基因遗传、基因多效性。 * **DNA的结构与拓扑:** DNA的A、B、Z构象,DNA拓扑学,双螺旋结构的原因,核苷酸碱基的排列,DNA的松弛状态、超螺旋及其重要性。 * **基因编辑技术:** meganuclease、zinc finger nuclease、TALENS、CRISPR、Cas9酶、向导RNA。 * **遗传性疾病与DNA修复:** 遗传性疾病,DNA修复通路(如非同源末端连接、同源重组修复)。 * **热门议题探讨:** 双胞胎并非100%相同的原因,兄弟姐妹间身高差异的原因,肤色多样性的成因,单一基因突变影响身体其他部位功能的原因。 完成本课程后,你将对从基础到高级的遗传学知识有清晰的理解,并有能力将所学概念应用于理解未来几代人的遗传模式。课程还包含奖励讲座和测验。

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课程详情

This course will help students learn the different concepts of Genetics like DNA, RNA, Types of RNA, Chromosomes, Chromatids, how to find the number of chromosome and chromatids in cell cycle different phases, what is evolution, Hereditary and variations, what is epigenetics, multiple alleles, Mendel's Laws, Law of dominance, law of segregation, law of independent assortment, what are factors, what is gene, What are the deviations from Mendel's law? Incomplete dominance, codominance, multiple alleles concept with ABO blood group How to draw punnet square what is genetic code, wobble hypothesis, polygenic inheritance, pleiotropy, DNA structure, conformations A, B, and Z forms, DNA topology, why DNA has double helical structure, CFTR gene, function and structure, gene editing techniques, meganuclease, zinc finger nuclease, TALENS, CRISPR, Cas 9 enzyme, guide RNA, Genetic Disorders, DNA Repair pathways, Non-homologous end joining method, homology repair pathways, etc.Not only this, but you will also get a bonus lecture and quiz.You will be able to apply these concepts practically to understand the inheritance pattern in future generations. Also, you will find the reality that twins are not 100% identical. Why? Also why in siblings one grows taller in height while other one remains short? Why are there so many varieties of skin tone and color present in the entire world population? or why does a mutation in one particular functional gene alter the function at some other part of the body? Why does DNA have a double-helical structure? Why are nucleotide bases found in between the two sugar-phosphate strands of DNA? Why does DNA exist in a relaxed state? What is supercoiling, and why is it so important? Why does DNA maintain its topology? What are different gene defects?You need to finish this course to get all the answers.After completing this course, we assure you that you will get a clear understanding of all the topics of genetics, from basics to advanced.I welcome you to enroll in this and other courses on my profile.Stay Safe!Stay Healthy!

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