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所在平台: Udemy |
课程主页: https://www.udemy.com/course/introductory-organic-chemistry-spectroscopy/
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课程名称：初级有机化学光谱学 课程概述：在本课程中，您将学习质谱法、红外光谱法（IR）、氢核磁共振（H-NMR）和碳核磁共振（C-NMR）的基本概念及其在识别有机化合物结构中的应用。 - **质谱法**：样品分子通过高能电子电离，测量这些离子的质荷比和分子的分子量。此外，离子碎片化模式可以与分子的结构相关联。 - **红外光谱法（IR）**：低能放射的吸收导致分子内原子团的振动和旋转激发。通过特征吸收，可以轻松识别各种功能团，如烷烃、烯烃、炔烃、醇、醛、酮、羧酸、腈、胺和酰胺。IR也可用于监测有机反应的进展。 - **核磁共振光谱法（NMR）**：在低能射频波段的吸收会导致核自旋状态的激发。高分辨率的氢和碳核磁共振谱能够区分分子中不同位置的氢和碳原子。通过氢核磁共振和碳核磁共振，可以验证分子结构并区分结构异构体，例如丙醇和乙基甲基醚。利用耦合常数，还可区分几何异构体，如顺式和反式异构体。 本课程将为您提供识别和解析有机化合物所需的光谱学基本工具和知识。
In this course, you will learn the basic concepts of Mass Spectrometry, IR Spectroscopy, H-NMR, C-NMR, and their applications to identify the structures of organic compounds. Mass Spectrometry: Sample molecules are ionized by high energy electrons. The mass to charge ratio of these ions and the molecular weight of the molecule are measured. Also, Ion fragmentation patterns may be related to the structure of the molecule.• Infrared Spectroscopy (IR): Absorption of this lower energy radiation causes vibrational and rotational excitation of groups of atoms within the molecule. Because of their characteristic absorptions, identification of various functional groups is easily achieved. The presence of the functional groups such as alkanes, alkenes, alkynes, alcohols, aldehydes, ketones, carboxylic acids, nitriles, amines, and amides can be verified by IR spectroscopy. IR is also used to monitor the progress of Organic Reactions. • Nuclear Magnetic Resonance Spectroscopy (NMR): Absorption in the low-energy radio-frequency part of the spectrum causes excitation of nuclear spin states. High-resolution H-NMR and C-NMR spectra distinguish H and C atoms in different locations in the molecule. Using H-NMR and C-NMR, you can verify the molecular structure and differentiate the structural isomers, for instance, between propanol and ethyl methyl ether. Also, using the coupling constants, you might distinguish the geometrical isomers such cis and trans isomers.
