Introduction to Medical Biochemistry

所在平台: Udemy

课程主页: https://www.udemy.com/course/introduction-to-medical-biochemistry/

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课程简介

**课程名称:** 基础医学生物化学导论 **课程概述:** 本课程是一系列入门级讲座,适合学生和爱好者。我们将深入探讨生物化学、分子生物学和遗传学的基本原理。 **主要内容:** * **DNA的奥秘:** 学习DNA的结构与功能,理解其如何编码遗传信息,以及DNA复制的过程。 * **蛋白质的合成与功能:** 探索DNA如何通过RNA合成蛋白质,以及这些蛋白质在维持细胞生命活动中的作用,重点关注酶和激素。 * **基因突变与疾病:** 了解基因突变的成因、表现形式及相关疾病。 * **分子生物学技术:** 学习用于实验目的的克隆技术,包括其原理、操作及在调控基因表达中的应用。 * **癌症的生物学:** 探讨癌症的本质及其转移机制。 * **理性药物设计:** 以小分子抑制剂伊马替尼为例,学习其设计原理和在治疗慢性髓性白血病中的作用。 * **CRISPR-Cas9基因编辑技术:** 了解CRISPR-Cas9的起源、工作原理及其在实验室中的广泛应用。 本课程将帮助您建立扎实的生物化学基础,为进一步学习生命科学领域打下坚实基础。

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课程详情

This is an introductory lecture series fit for students and hobby learners alike. During the course you will cover the basics of biochemistry, molecular biology and genetics. You will explore the structure and function of DNA, taking a look at what it is and how it is structured to create the genetic code, as well as how it replicates. You will see how proteins are made from DNA using RNA and how these proteins function to keep life sustained in different types of cells while taking a closer look at enzymes and hormones. You will take a look at mutations and see how they manifest and what causes them, while exploring some of the diseases which are associated with them. Next, you will explore the process of cloning for experimental purposes, what it involves, how it works and how it is applied in the laboratory to affect gene expression. You will take a look at the what cancer is and how it metastasises. Following this, you will explore small molecule drug design (rational drug design) focussing on the small molecule inhibitor Imatinib. Here your will take a look at how it was designed and how it functions to help patients with chronic myeloid leukaemia. Finally, you will explore CRISPR-Cas9, what it is and how it was discovered taking a look at its applications in the laboratory.

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