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所在平台: Udemy |
课程主页: https://www.udemy.com/course/introduction-to-drug-development-and-discovery/
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**课程名称：** 药物开发与发现导论 **课程概述：** 本课程将深入浅出地介绍药物开发和发现的复杂过程。从最初的分子靶点研究与发现，到后期的人体试验，药物测试是一个需要高度谨慎的创新过程，也是一项耗时且成本高昂的探索。 课程内容涵盖： * **早期阶段：** 体外试验（针对细胞）、计算机辅助分析（in silico 试验）、表型测试与机制测试的区别。 * **动物试验：** 介绍不同动物模型的选择及其主要差异。 * **人体临床试验：** 详细讲解人体试验的进行方式。 * **特定领域应用：** 探讨癌症、传染病等不同疾病背景下的药物发现。 * **疫苗开发：** 专门设有一部分介绍疫苗的开发，并重点解析新冠疫苗的工作原理。 **课程单元：** 1. 引言 2. 体外试验：细胞化合物测试 3. 计算机辅助试验：计算分析助力过程 4. 体内试验：实验室动物实验 5. 临床试验：人体测试 6. 疫苗开发导论 7. 附加章节 **学习目标：** 完成本课程后，您将能够： * 了解药物发现的全过程。 * 区分药物研发中进行的各类实验。 * 掌握动物模型在药物发现中的优势与特点。 * 理解人体临床试验的开展方式。 * 认识疫苗的开发过程。
Drug development is often a long and complicated process. From the initial phase, with the research and discovery of molecular targets, to tests with human beings, in later phases, drug tests constitute an innovation process where great care needs to be taken. It comprises one of the most laborious and costly processes of discovering new things.This course is an introduction to the drug discovery process, explaining from the initial phases, such as in vitro tests, the difference between phenotypic and mechanistic tests, through animal tests, with the main difference between used animal models, to the tests clinics in human beings, with explanations about different drug discovery situations, such as specific contexts for cancers, for infectious diseases. The course has a session dedicated to the development of vaccines, with a certain emphasis on how COVID-19 vaccines work, for example.The course is divided into the following sessions:1- Introduction2- In vitro tests: testing compounds in cells3- In silico tests - computational analysis helping the process4- In vivo tests - experiments on laboratory animals5 - Clinical tests - Tests performed on human beings6 - Introduction to vaccine development7 - Extra sectionThis course is an introduction to the drug discovery process, explaining from the initial phases, such as in vitro tests, the difference between phenotypic and mechanistic tests, through animal tests, with the main difference between used animal models, to the tests clinics in human beings, with explanations about different drug discovery situations, such as specific contexts for cancers, for infectious diseases, and also the development of vaccines, with a certain emphasis on how COVID-19 vaccines work, for example.So, if you are interested in knowing...a. How a drug discovery process is carried outb. Different types of experiments conducted in drug discoveryc. What are the advantages and features of animal models for drug discoveryd. How are clinical (human) trials conductede. How vaccines are developed...then, I think this course is for you!
