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所在平台: Udemy |
课程主页: https://www.udemy.com/course/introduction-to-cell-signaling/
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课程名称：细胞信号传导入门 课程概述：本课程将介绍细胞信号传导的基础知识，包括信号传导的组成部分，如受体、转导分子及其机制、第二信使、不同酶（如激酶）对蛋白质磷酸化的机制，以及反转信号的机制（如磷酸酶和磷酸二酯酶）。此外，还将探讨信号酶的别构调节、人类体内的不同信号通路、信号交叉谈话、研究信号的现代方法、细胞凋亡的过程、细胞周期的调控、信号在人体疾病中的失调、靶向信号蛋白以进行疾病治疗的策略等。 课程目标是：提供细胞信号传导的当前概念概述；介绍信号分子及其受体；帮助学生理解信号通路和网络；阐明转导分子及其机制；提供第二信使的概念。 推荐教材包括《细胞的分子生物学》（Elberts et al. 2008年，第五版）以及《信号转导与调控生物化学》（Gerhaurd Krauss 第三版）。此外，在线资源也将为细胞信号传导和生物学提供支持。 细胞并不是静态的，它们能够感知周围环境，并实时响应邻近细胞和环境的提示。此刻，您的细胞正以化学信号分子的形式发送和接收数以百万计的信息。细胞通常通过化学信号进行交流，这些信号通常是由发送细胞产生的蛋白质或其他分子，并从细胞中分泌到细胞外空间，随后漂浮到邻近细胞中。 本课程将帮助学生对细胞信号传导的各个方面有一个全面的了解，奠定细胞生物学和生物化学的基础。
introduction to cell signaling , components of cell signaling which include receptors , trasnducers and their machanism, second messenger, machanism of protein phosphorylation by different enzymes like kinases, reversing signals like phosphatases and phosphodiesterases etc. allosteric regulation of signaling enzyme, different signaling pathways accuring in human body, signaling cross talk, modern method to study signaling, process of apoptosis, regulation of cell cycle, deregulation of signaling in human diseases, targeting signaling proteins for disease theraupeutics, our objectives areto provide an overview of current concepts of cell signalingto introduce the student about signaling molecule and their receptorsto develop understanding about signaling pathways and networkto give the concept of transducers and their machanismproviding concept of second massengerrecommended books for this course aremolecular biology of the cell( elberts et al 2008 5th edition)biochemistry of signal transduction and regulation ( gerhaurd krauss 3rd edition)online resources for cell signaling and biologyCells are not unconscious and static as bricks in a wall. Cells can detect what's going on around them, and they can respond in real time to cues from their neighbors and environment. At this very moment, your cells are sending and receiving millions of messages in the form of chemical signaling molecules!Cells typically communicate using chemical signals. These chemical signals, which are proteins or other molecules produced by a sending cell, are often secreted from the cell and released into the extracellular space. There, they can float over to neighboring cells.
