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所在平台: Udemy |
课程主页: https://www.udemy.com/course/gmp-pharmaceutical-tablet-manufacturing/
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课程名称：GMP：制药片剂制造 课程概述： 片剂是最重要的可压缩固体剂型之一，压缩片剂是目前使用最广泛的剂型。约有三分之二的处方以固体剂型发放，其中一半为压缩片。片剂可以被制成传递准确剂量的形式，通常口服，但也可以舌下、颊部、直肠或阴道给药。设计、开发和优化高质量片剂的制造工艺在制药剂型开发过程中起着至关重要的作用。理解这些制造过程为我们提供了科学的视角，以解决制造问题，提高生产效率，并支持商业目标。制药过程的设计、开发和优化对于制药行业中剂型的开发非常重要。本课程将帮助您理解制药片剂的制造过程，以及制药制造在研发和商业生产阶段的基本概念和实际应用。 课程内容： 1. 介绍 2. 可压缩固体剂型 3. 片剂（片剂、嚼片、泡腾片） 4. 薄膜涂层片（糖衣片、薄膜涂层片、肠溶片） 5. 制药辅料 5.1 稀释剂 5.2 粘合剂 5.3 崩解剂 5.4 润滑剂 6. 固体剂型的制药制造方法 7. 直接压片（干混合） 7.1 直接压片的一般定义 7.2 直接压片的优点 7.3 直接压片的缺点 8. 造粒 8.1 造粒的一般定义 8.2 造粒的优点 8.3 造粒的缺点 9. 片剂压缩 10. 薄膜涂层 10.1 一般信息 10.2 薄膜涂层工艺 10.3 薄膜涂层设备 11. 结论 通过本课程，学员将获得制药片剂制造的系统知识，帮助提升其在相关领域的专业技能。
Tablets are one of the most important compressible solid dosage forms. The compressed tablet is the most popular dosage form in use today. About two-thirds of all prescriptions are dispensed as solid dosage forms, and half of these are compressed tablets. A tablet can be formulated to deliver an accurate dosage to a specific site; it is usually taken orally, but can be administered sublingually, buccally, rectally or intravaginally.Especially, designing, developing and optimizing of manufacturing process of tablet at a high quality play an essential role in pharmaceutical dosage form development process. To understand this manufacturing processes provides us rational and scientific view to solve manufacturing problems, increase our productivity and support our commercial aims. Design, development and optimization of pharmaceutical process and manufacturing strategies are very important for the development of a pharmaceutical dosage forms in the pharmaceutical industry. This course will help you to understand pharmaceutical tablet manufacturing process with basic concepts of technical and practical applications of pharmaceutical manufacturing in the research and development phase and commercial manufacturing period.PHARMACEUTICAL TABLET MANUFACTURING COURSE CONTENT1_Introduction 2_Compressible Solid Dosage Form 3_Tablet (Tablet, Chewable Tablet, Effervescent Tablet) 4_Film Coated Tablet (Sugar Coated, Film Coated, Enteric Coated Tablet) 5_Pharmaceutical Excipients 5_1_Diluent 5_2_Binder 5_3_Disintegrants 5_4_Lubricants 6_Pharmaceutical Manufacturing Methods for Solid Dosage Forms 7_Direct Compression (Dry Mixing) 7_1 General Definition of Direct Compression 7_2 Advantageous of Direct Compression 7_3 Disadvantageous of Direct Compression 8_Granulation 8_1 General Definition of Granulation 8_2 Advantageous of Granulation 8_3 Disadvantageous of Granulation 9_Tablet Compression10_Film Coating 10_1 General Information 10_2 Film Coating Process 10_3 Film Coating Equipment 11_Conclusion
