Genetics

所在平台: Udemy

课程主页: https://www.udemy.com/course/genetics-bsc/

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课程简介

**课程名称:遗传学** **课程概述:** 本课程旨在帮助学生系统学习遗传学的基本概念和重要理论,涵盖以下九个单元: * **第一单元:遗传学基础概念** - 深入理解DNA和RNA的结构,包括核苷酸、糖和磷酸基团,以及DNA分子中的碱基互补配对原则和反向平行链结构。 * **第二单元:孟德尔遗传定律** - 学习孟德尔为何选择豌豆进行实验,详细讲解单性杂交和双性杂交,并提供相关的解题方法。还将探讨不完全显性及其典型案例。 * **第三单元:基因互作** - 探讨多种基因互作类型,如上位性(Epistasis)、复等位基因(Multiple Allelism)及其案例,以及多基因遗传(Polygenic Inheritance)。学生将有机会练习复等位基因相关问题的解答。 * **第四单元:性别决定** - 学习植物和动物的性别决定机制,包括异配性别雄性(Heterogametic Male)及其不同类型,以及异配性别雌性(Heterogametic Female)及其不同类型,并提供具体范例。 * **第五单元:连锁与交换** - 详细介绍遗传交换(Crossing over)的机制、同源染色体间的完全连锁和不完全连锁(以果蝇和玉米为例)。还将阐述连锁的连锁与互斥假说,以及摩尔根(Morgan)的连锁观点。 * **第六单元:染色体结构与数目变异** - 学习染色体结构变异的各种类型,如缺失(Deletion)、倒位(Inversion)、重复(Duplication)、易位(Translocation)和串联重复(Tandem duplication)。还将探讨染色体数目变异,包括同源多倍体(Autopolyploid)和异源多倍体(Allopolyploid)的概念,并通过新大陆棉花(New World Cotton Plant)的例子进行深入解析。 * **第七单元:细胞质遗传** - 探讨细胞质遗传现象,包括紫茉莉(Mirabilis jalapa)的母性遗传,酵母的矮小基因(Petite characters in yeast),以及喇叭虫(Paramecium)的Kappa颗粒(Kappa Particles in Paramecium)。 * **第八单元:突变与诱变剂** - 学习突变的类型和诱发突变的因素,包括物理、化学和生物诱变剂。还将深入研究点突变(Point mutation)和移码突变(Frame shift mutation),以及基因突变中的转换(Transition)、颠换(Transversion)和互变异构(Tautomerism)。 * **第九单元:染色体异常综合征** - 介绍多种由染色体异常引起的综合征,如特纳氏综合征(Turner's Syndrome)、唐氏综合征(Down Syndrome)、猫叫综合征(Cri du chat Syndrome)和克兰费尔特氏综合征(Klinefelter's Syndrome)。

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课程详情

In this course students will be able to understand UNIT -1Basics concept of GeneticsStructure of DNA and RNA, Nucleotide, Sugar and Phosphate Complimentary Base Pairing and Antiparallel Strands present in DNA UNIT - 2Learn about the Mendelian law of InheritanceWhy he chose Pea plants for his Experiments we will study about Monohybrid cross and Dihybrid cross Problems to solve on Monohybrid and Dihybrid cross Incomplete Dominance with an exampleUNIT - 3Different Types of Gene Interaction like Epistasis, Multiple Allelism with example and Polygenic InheritanceStudents can solve Problem on Multiple AllelismUNIT- 4Sex determination in plants and animals Heterogametic Male and its types Heterogametic Female and its types with an Example UNIT - 5Crossing over and its mechanismComplete linkage and in complete linkage seen in Drosophila and maize Coupling and repulsion hypothesis on Linkage Morgan view on linkage UNIT- 6Structural changes seen in chromosome like Deletion, Inversion, Duplication, Translocation and Tandem duplication Numerical changes seen in chromosome related to Autopolyploid and Allopolyploidwe will study in detail about Autopolyploid and allopolyploid with an example of New World Cotton PlantUNIT - 7Maternal Inheritance seen in Mirabilis jalapaPetite characters in yeast Kappa Particles in ParameciumUNIT- 8Mutation and MutagensPhysical, Chemical and Biological MutagensPoint mutation and Frame shift mutationGene mutation like Transition, Transversion and TautomerismUNIT - 9Different types of Syndromes like turners, Down, Cri du chat and Klinefelter's Syndrome

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