Genetics and Next Generation Sequencing for Bioinformatics

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课程主页: https://www.udemy.com/course/genetics-and-next-generation-sequencing-for-bioinformatics/

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课程简介

Coursera 课程总结:**遗传学与下一代测序技术在生物信息学中的应用** **课程概览:** 本课程旨在为希望进入生物信息学领域的学员提供坚实的遗传学基础,并深入介绍下一代测序(NGS)技术及其在个性化癌症治疗和疾病研究中的应用。学员将了解DNA、RNA和遗传学的基本原理,并掌握NGS数据分析的核心概念。 **课程亮点:** * **扎实的生物学基础:** 建立对DNA、RNA和遗传学的全面理解。 * **NGS数据分析入门:** 深入了解下一代DNA测序分析的技术和方法。 * **实践操作:** 利用云平台Galaxy进行大规模数据集分析。 * **数据质量控制:** 学习评估原始数据质量,并使用FastQC和Trimmomatic提高数据质量。 * **项目实践:** 完成一个指导性项目,对Illumina测序的原始数据进行质量评估和优化。 **先修要求:** * 高中十年级水平的生物和化学基础。 * 基本的统计学知识(如图表、直方图和箱线图的解读)。 * 对生物学有浓厚兴趣。 **目标学员:** 本课程适合对NGS数据分析零基础且希望开启生物信息学职业生涯的初学者。 **课程定位:** 这是NGS领域的入门课程,涵盖了生物学先修知识和质量控制。后续课程将深入探讨数据分析的更多细节。

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课程详情

Do you want to enter the field of Bioinformatics, but don't know enough about DNA, RNA, and Genetics?Are you curious about the recent advances in DNA sequencing technology, and how it can be applied to Personalized Cancer Therapy and Disease Research?Do you want to use Bioinformatics tools to analyze data generated by Next Generation Sequencing?By the end of this course:You will have a strong foundation in DNA, RNA, and GeneticsYou will have a thorough understanding of Next Generation DNA Sequencing AnalysisYou will use a cloud-based platform called Galaxy for the analysis of large datasetsYou will assess the quality of raw dataYou will use FastQC and Trimmomatic to improve data qualityThis course is a starting point in NGS. It covers Biology prerequisites and quality control. Future courses will cover data analysis in more detail.Project:This course includes a step-by-step guided project.This project will assess the quality of raw data from an Illumina sequencer.You will then use FastQC and Trimmomatic to improve the quality of this data.Prerequisites:Biology and Chemistry at high school 10th grade levelElementary Statistics such as interpreting charts, histograms, and box-and-whisker plotsYou must enjoy BiologyThis is an introductory course ideal for those with no prior experience in Next Generation Sequencing Analysis.Enroll today, and launch your career in Bioinformatics.

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