Enrichment analysis: interpret gene lists like a pro

所在平台: Udemy

课程主页: https://www.udemy.com/course/gene-enrichment-analysis/

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课程简介

## 课程总结:基因富集分析——专业解读基因列表 本课程是关于基因富集分析的简短介绍,这是将本体、通路和转录因子分配给高通量实验产生的基因列表的最常用系统方法。 **核心内容:** * **介绍两种常用的定位大型基因列表共有特征的方法。** * **提供使用 GeneTrail(基因集富集分析)和 WebGestalt(过表达分析)这两个常用网络工具进行实际分析的机会。** * **包含书面材料、视频讲解、准备好的实例数据文件等学习资源。** * **通过模拟生物学家与生物信息学家之间的讨论,澄清分析中的常见误解。** * **由两位活跃的研究领域专家提供指导。** * **通过小测验巩固学习效果。** **学习目标:** * 熟练掌握基因富集分析的两种主要方法。 * 能够独立使用 GeneTrail 和 WebGestalt 进行基因列表分析。 * 理解基因富集分析在研究中的应用场景和注意事项。 **学习建议:** * **适合人群:** 拥有分子生物学研究背景的学习者,或对该领域有基本了解的学习者。 * **学习时间:** * 具有分子生物学研究背景者:8-10小时的积极学习时间。 * 仅有领域概况了解者:需要更多背景材料学习和练习,可在几天内完成。 * **推荐学习周期:** 建议在一周内完成所有课程材料,以最大化学习效率。 **课程价值:** * **提升技能:** 学习在生物信息学和数据分析领域高度需求的技能。 * **拓展潜力:** 掌握这些易于使用但非常有用的工具,能够增强您作为研究人员的未来潜力,尤其是在分子生物学和制药行业。

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Gene enrichment analysis is the most popular systematic approach to assign ontologies, pathways, and transcription factors to gene lists usually resulted from high throughput experiments. This short course introduces the two most frequently applied methods to locate the common features of large gene lists, and provide opportunities to practice this analysis in the most common research scenarios using GeneTrail (for gene set enrichment analysis) and WebGestalt (for over-representation analysis), the two web tools used most often in the field. You get written material, video explanations for the background, and prepared example data files for practices. You are provided with (almost) real life discussions between a wet-lab biologist and a bioinformatician to clarify the most common misunderstandings related to this analysis. You are led step by step by two experts of the field, both active researchers; and in the meantime, you are challenged to proof your knowledge in quizzes. If you have a solid background in molecular biology research, you will be able to expert these methods in a maximum of 8-10 active course hours, but if you have only a general idea of the field, you will get a plenty of background material to learn and practice all in a few days. We recommend to cover all the provided material approximately in a week to maximize the efficiency of your learning. As you know, bionformatics and data analysis skills are highly demanded among molecular biology and pharma researchers. Why not equip yourself with these easy but very useful tools to extend your future potential as a researcher?

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