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所在平台: Udemy |
课程主页: https://www.udemy.com/course/dna-structure/
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**课程名称：DNA 结构** **课程概述：** 本课程深入探讨了 DNA 的基本结构及其在生命体内的重要作用。DNA 不仅是遗传信息传递的载体，还在蛋白质合成过程中扮演着关键角色。课程重点介绍了核 DNA、线粒体 DNA 和质体 DNA 的概念及其特点。 * **核 DNA：** 存在于真核生物细胞核内，编码了大部分基因组信息。 * **线粒体 DNA：** 位于细胞线粒体中，由母亲遗传给后代，人类线粒体 DNA 约有 16,000 个碱基对。 * **质体 DNA：** 存在于质体中，对光合作用至关重要。 **DNA 类型：** 课程详细阐述了三种主要的 DNA 结构类型： * **A DNA：** 与 B DNA 类似，为右旋双螺旋。在脱水等极端条件下，DNA 可形成 A 型以获得保护，蛋白质结合时也会导致 DNA 形成 A 型。 * **B DNA：** 最常见的 DNA 构象，为右旋双螺旋。在正常生理条件下，大多数 DNA 呈现 B 型构象。 * **Z DNA：** 左旋双螺旋，以锯齿状模式向左扭曲。由 Andrew Wang 和 Alexander Rich 发现，存在于基因起始位点前方，可能与基因调控有关。 **教学形式：** 本课程的所有概念都将以 PPT 演示文稿的形式清晰呈现，便于学习和理解。
Apart from being responsible for the inheritance of genetic information in all living beings, DNA also plays a crucial role in the production of proteins. Nuclear DNA is the DNA contained within the nucleus of every cell in a eukaryotic organism. It codes for the majority of the organism's genomes while the mitochondrial DNA and plastid DNA handles the rest.The DNA present in the mitochondria of the cell is termed as mitochondrial DNA. It is inherited from the mother to the child. In humans, there are approximately 16,000 base pairs of mitochondrial DNA. Similarly, plastids have their own DNA and they play an essential role in photosynthesis.DNA typesThere are three different DNA types:A DNA It is a right handed double helix similar to the B DNA form. Dehydrated DNA takes an A form that protects the DNA during extreme condition such as desiccation. Protein binding also removes the solvent from DNA and the DNA takes a form.B DNA This is the most common DNA conformation and is a right-handed helix. Majority of DNA has a B type conformation under normal physiological conditions. Z DNA is a left-handed DNA where the double helix winds to the left in a zig-zag pattern. It was discovered by Andres Wang and Alexander Rich. It is found ahead of the start site of a gene and hence, is believed to play some role in gene regulation.all concepts covered clearly on ppt level presentation.
