Biotechnology: Antibodies & their role in Therapeutics

所在平台: Udemy

课程主页: https://www.udemy.com/course/biotechnology-antibodies-their-role-in-therapeutics/

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课程名称:生物技术:抗体及其在治疗中的作用 课程概述:免疫系统是人体抵御入侵病原体和毒素的自身防线,类似于一个国家的防务力量。在众多的细菌、病毒、寄生虫和毒素中,我们的免疫系统起着保护身体的重要作用。抗体(也称为免疫球蛋白)是免疫系统中重要的战士之一,负责抵抗这些有害病原体。如果缺乏抗体,各种病原体可能会攻击神经细胞、肾细胞、心脏细胞等重要组织,导致严重的疾病。而抗体的作用是通过结合病原体来阻止其攻击身体细胞。 本课程面向医学学生、医生以及生物技术、生物学、免疫学、遗传学、分子生物学、细胞生物学和生物信息学等学科的学生。课程将以简单易懂的动画和图形形式呈现最复杂的概念,帮助学习者理解抗体的结构、类型及其功能。 课程内容包括: - 不同类型的抗体及其在血液和组织液中的作用 - 生成抗体的遗传机制及免疫系统对多种抗原的反应 - 类切换机制、膜结合形式与分泌形式抗体的表达及免疫球蛋白基因的调控 - 被动免疫与主动免疫的定义和区别 - 多克隆抗体与单克隆抗体的不同 - 杂交瘤技术及其在大规模生产单克隆抗体中的应用 - 治疗性抗体的种类:嵌合单克隆抗体、人体化单克隆抗体和全人单克隆抗体 - 抗体结构在癌症、关节炎及其他病毒、荷尔蒙和自身免疫疾病治疗中的应用 - 恢复期血浆治疗(被动抗体治疗)及其在COVID-19治疗中的应用 - 抗体在治疗和诊断中的相关性 课程提供30天的退款政策,如果不满意可以退费。参与该课程的人士将能够获得有关抗体及免疫系统的深入知识。 适合人群: - 医学学生、医生、研究人员以及生物、免疫学、生物技术等领域的学生 - 学习免疫系统相关课程的学生 - 有意在大学学习生物学或免疫学的学生 - 需要抗体相关优质资源的新教师 - 希望深入了解抗体和免疫系统的任何人 本课程是一个宝贵的学习资源,期待您的加入。

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课程详情

Immune system is the body's own army that fights against the invading pathogens and toxins. You can compare it to a nation's defense forces. The army, the air force and the navy all work for the nation's defense. Similarly, the immune system works for the body's defense. Everywhere around us, there are dangerous bacteria, viruses, parasites and toxins that can attack and harm our body. But our immune system defends us from these pathogens.Antibodies, also known as immunoglobulins, are one of the crucial warriors produced by our immune system to fight off these nasty invading pathogens. In absence of antibodies, these pathogens can attack our nerve cells, kidney cells, heart cells and other vital parts of the body.Once attacked by these nasty pathogens, the cells stop functioning, which in turn, may lead to serious illness. But when antibodies come into action, everything changes. They bind to the invading pathogens and prevent them from attacking our body cells.So what do these antibodies look like, what is their structure and how do they fight off such dangerous pathogens? If you are also curious about these concepts and want to learn the science behind it, then you have come to the right place.This course is an invaluable resource for medical students, doctors and students of disciplines like biotechnology, biology, immunology, genetics, molecular biology, cell biology and bioinformatics. In the course, the most challenging concepts are presented in a simple and palatable format using animations and graphics.This course will cover different types of antibodies circulating in the bloodstream & tissue fluids and their respective functions. Additionally this course will also cover the genetic mechanisms which allow our immune system to generate such a diverse pool of antibodies because of which our body is able to recognize and respond to a variety of antigens.Further in this course, the class switching mechanism, expression of membrane bound & secreted forms of antibodies and regulation of expression of immunoglobulin genes have also been discussed.Moreover, you will also get to know what is passive immunity and what is active immunity.We will also discuss the differences between polyclonal and monoclonal antibodies. In this course, the hybridoma technology has been discussed in detail and how it can be used to mass produce monoclonal antibodies? And how monoclonal antibodies can be used as therapeutics?Additionally this course will introduce you to various engineered therapeutic antibodies like chimeric monoclonal antibodies, humanised monoclonal antibodies and fully human monoclonal antibodies. In this course, you will get to know how the antibody structure can be leveraged to create immunotoxins, bispecific antibodies, abzymes etc for the treatment of cancer, arthritis, other viral, hormonal and autoimmune diseases.In this course we will discuss what is convalescent plasma therapy or passive antibody therapy and how it is being used for the treatment of COVID-19 disease, the current ongoing pandemic. Last but not the least, the course will also highlight the relevance of antibodies in therapeutics and diagnostics.With a 30 day return policy, there is nothing to lose. If you feel the course is not worth your money, you can return it and get your money back. Though, we assure you that you will not be disappointed by your wise decision of enrolling in this course.Who this course is for:The course is designed for medical students, doctors, researchers and students of biology, immunology, biotechnology, genetics, molecular biology, cell biology and bioinformatics disciplinesAny student who has immune system as a subject in their curriculumAnyone looking to study biology or immunology at college or university and wants quick, to the point knowledge about antibodiesNewly qualified teachers who need some great resources on antibodiesAnyone who wants to get an in-depth knowledge about antibodies and our immune system

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