Bioinformatics; Learn Docking & Mol Dynamics Simulation

所在平台: Udemy

课程主页: https://www.udemy.com/course/bioinformatics_advance/

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课程简介

**Coursera 课程总结:生物信息学 - 学习分子对接与分子动力学模拟** 本课程是一门面向生物学家的高级生物信息学课程,全面讲授分子对接(Ligand-Protein Docking)和分子动力学模拟(Molecular Dynamics Simulation)的理论与实践。课程从零开始,即使是初学者也能轻松跟上。 **课程亮点:** * **理论与实践并重:** 深入浅出地讲解两种技术的核心原理,并通过详细的实际操作演示,帮助学习者掌握实际操作技能。 * **广泛的工具教学:** 课程使用多种开源免费的软件工具,包括 Modeller, I-TASSER, Alpha-Fold (Colab), Auto-dock4, Vina, Patch-Dock, GROMACS, LigPlot, ChemSketch, OpenBabel, Pymol 等,确保学习者无需额外购买昂贵软件即可实践。 * **全面覆盖内容:** 1. 蛋白质结构生物信息学 2. 分子动力学模拟理论 3. Linux 环境入门 4. 蛋白质分子动力学模拟实践 5. 配体-蛋白质对接(理论与实践) 6. 配体-蛋白质复合物分子动力学模拟实践 7. 使用 Vina 对配体与蛋白质进行虚拟筛选 * **易于入门:** 课程内容设计简洁明了,特别适合对生物信息学领域感兴趣的初学者。 * **强大的支持:** 课程提供全程的答疑和支持,确保学习者的学习过程顺利。 完成本课程后,学习者将能够熟练运用分子对接和分子动力学模拟技术,为生物学研究提供有力的工具支持。

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Currently, there is high use of bioinformatics tools in biological studies. This Advance Bioinformatics course includes theory and practical aspects of molecular docking and molecular dynamics simulation for you. In this course, we have tried to explain the theory and practical steps which are required to perform the above-mentioned bioinformatics techniques. We strongly believe that after having this course, you will be well versed in ligand-protein docking and molecular dynamics simulations. This course is designed to keep the need of biologists in view. We tried to explain every step in a simple and elegant way. Like our previous course, "Learn Bioinformatics From Scratch (Theory & Practical)" in this course, we took start from scratch. So, if you are new in this field then it will be easy for you to move with the flow. There is a total of seven modules with 104 lectures. In this course, you will learn (1) Protein Structural Bioinformatics (2) Theory of Molecular Dynamics Simulation (3) Introduction of Linux Environment (4) Practical Demonstration of Protein Molecular Dynamics Simulation(5) Ligand-Protein Docking (Theory & Practical)(6) Practical Demonstration of Ligand-Protein Complex Molecular Dynamics Simulation(7) Virtual Screening of Ligands with Protein Using VinaThis course is a unique blend of theory and practical. We assure you that after having this course, performing molecular docking and molecular dynamics will be easy for you. We have used open-source software in this course so that you do not need to purchase any expensive software. The tools which are demonstrated in this course are Modeller, I-TASSER, Alpha-Fold (Colab), Auto-dock4, Vina, Patch-Dock, GROMACS, LigPlot, ChemSketch, OpenBabel, Pymol, and a lot more. These tools are freely available and closely related to the course material, and students will need to sign up for some tools to access it. So what are you waiting for? Click the enroll button and start this amazing journey. We hope that the content of this course will be worth your money. We assure every possible assistance throughout your learning process. We always respond to Questions and Queries which you will forward to us. We believe that we will grow with you. Your growth is our growth.

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