开始时间: 04/22/2022 持续时间: 未知
所在平台: MIT公开课 课程类别: 生物与生命科学 大学或机构: ocw |
课程主页: http://ocw.mit.edu/courses/biology/7-342-g-protein-coupled-receptors-vision-and-disease-spring-2007
课程评论:没有评论
How do we communicate with the outside world? How are our senses of vision, smell, taste and pain controlled at the cellular and molecular levels? What causes medical conditions like allergies, hypertension, depression, obesity and various central nervous system disorders? G-protein coupled receptors (GPCRs) provide a major part of the answer to all of these questions. GPCRs constitute the largest family of cell-surface receptors and in humans are encoded by more than 1,000 genes. GPCRs convert extracellular messages into intracellular responses and are involved in essentially all physiological processes. GPCR dysfunction results in numerous human disorders, and over 50% of all prescription drugs on the market today directly or indirectly target GPCRs.