Medicinal Chemistry: The Molecular Basis of Drug Discovery

开始时间: 04/22/2022 持续时间: 7 weeks

所在平台: EdxArchive 课程类别: 其他类别 大学或机构: davidsonx 授课老师： Erland Stevens

课程主页: https://www.edx.org/archive/medicinal-chemistry-molecular-basis-drug-davidsonx-d001x-1

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课程详情

This medicinal chemistry course explores how chemists modify a molecule’s structure to design a safe and effective drug.

This course opens with a brief history of drug discovery and introduces the modern drug approval process. Then, we will transition to learning about receptors and enzymes, the body’s molecules most often targeted by drugs. We will also discuss the topics of pharmacokinetics (drug adsorption, elimination, and half-life) and metabolism. The course closes with units on how potential drug molecules are identified and subsequently optimized into safe and effective drugs.

课程大纲

• How to measure the activity of enzymes and receptors
• Methods for modeling a drug’s half-life
• How to predict and alter the metabolism of a molecule
• Techniques for discovering molecules with desired biological activity
• Approaches for optimizing a molecule into a safe and effective drug

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This course is offered through a collaboration between DavidsonX and the Novartis Institutes of BioMedical Research.

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