Molecular Biology: DNA Replication and Repair

所在平台: EdxArchive

课程类别: 其他类别

大学或机构: MIT

授课老师: Stephen P. Bell Tania A. Baker

课程主页: https://www.edx.org/archive/molecular-biology-dna-replication-repair-mitx-7-28-1x

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课程大纲

  • How to compare and contrast the mechanisms of DNA replication in prokaryotes and eukaryotes
  • How to describe several enzymatic mechanisms that the cell uses to repair or tolerate DNA damage
  • How to analyze protein structures to infer functional information
  • Design methods for the best experiment to test a hypothesis related to DNA replication or repair proteins
  • How to interpret data from DNA replication and repair experiments

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课程详情

*Note - This is an Archived course*

You’re acquainted with your DNA, but did you know that your cells synthesize enough DNA during your lifetime to stretch a lightyear in length? How does the cellular machinery accomplish such a feat without making more mistakes than you can survive? Why isn’t the incidence of cancer even higher than it is? And, if the DNA in each and every cell is two meters long, how is this genetic material compacted to fit inside the cell nucleus without becoming a tangled mess?
 
Are you ready to go beyond the “what" of scientific information presented in textbooks and explore how scientists deduce the details of these molecular models?
 
Take a behind-the-scenes look at modern molecular genetics, from the classic experimental events that identified the proteins involved in DNA replication and repair to cutting-edge assays that apply the power of genome sequencing. Do you feel confident in your ability to design molecular biology experiments and interpret data from them? We've designed the problems in this course to build your experimental design and data analysis skills.
 
Let’s explore the limits of our current knowledge about the replication machinery and pathways that protect the fidelity of DNA synthesis. If you are up for the challenge, join us in 7.28x Part 1: DNA Replication and Repair.
 
Follow the latest news from MITx Biology @MITxBio on Twitter.

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This is a past/archived course. At this time, you can only explore this course in a self-paced fashion. Certain features of this course may not be active, but many people enjoy watching the videos and working with the materials. Make sure to check for reruns of this course.

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