Introduction to Bioconductor

开始时间: 04/22/2022 持续时间: 4 weeks

所在平台: EdxArchive 课程类别: 其他类别 大学或机构: Harvard University 授课老师： Rafael Irizarry Vincent Carey

课程主页: https://www.edx.org/archive/introduction-bioconductor-harvardx-ph525-4x

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课程详情

We will cover some common uses of the software packages within the Bioconductor project. You will get to decide if you learn methods for next generation sequencing, microarrays or both. We will cover a number of normalization, batch correction, and testing methods for high throughput data.

Topics:

• Intro to Biology
• Next Generation Sequencing
  •   GRanges, Rsamtools
  •   Statistical modeling of counts
  •   Differential expression of counts
• Microarrays
  •   eSets
  •   Background correction
  •   Differential expression of arrays
• Normalization
• Advanced differential expression
• Batch effects
• Gene set testing

This class was supported in part by NIH grant R25GM114818.

This course is part of a larger set of 8 total courses running Self-Paced through September 15th, 2015:

PH525.1x: Statistics and R for the Life Sciences

PH525.2x: Introduction to Linear Models and Matrix Algebra

PH525.3x: Advanced Statistics for the Life Sciences

PH525.4x: Introduction to Bioconductor

PH525.5x: Case study: RNA-seq data analysis

PH525.6x: Case study: Variant Discovery and Genotyping

PH525.7x: Case study: ChIP-seq data analysis

PH525.8x: Case study: DNA methylation data analysis

HarvardX pursues the science of learning. By registering as an online learner in an HX course, you will also participate in research about learning. Read our research statement to learn more.

课程大纲

• How to use the Bioconductor project software packages
• Methods to analyze data from next generation sequencing and microarray technologies

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