Useful Genetics

开始时间: 04/22/2022 持续时间: 6 weeks

课程主页: https://www.coursera.org/course/usefulgenetics

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课程详情

Image source: XKCD

Who might want to take this course?

• People affected by or concerned about a genetic disease (either directly or in a family member)
• People interested in the genetic diversity of humans or other species
• People who have had (or are considering having) their genes or genomes analyzed by companies such as 23andMe or DecodeMe
• People concerned about the public use of personal genetic information
• People interested in breeding animals or plants, or in in conservation of endangered species
• People interested in genealogy and ancestry analysis
• Science teachers
• Anyone interested in genetics but unable to enroll in university at this time

课程大纲

Part 1.  Genes and their effects

Week 1. How different are we?  Introduction to DNA, genes and chromosomes and the relationships between human populations.

Week 2. How DNA molecules change.  The causes and consequences of mutations.

Week 3. DNA differences and gene functions.  How genetic differences affect the activities of individual genes.

Week 4.  Predicting the effects of genetic differences.  How interactions between different genes determine their effects; genetics of cancer.

Week 5.  Personal genomics.  Kinds of DNA typing and genome analysis, and what can be learned from them.

Part 2.  Inheritance

Week 6.  The mechanics of inheritance.  How genes and chromosomes are transmitted through the generations.

Week 7.  Inheritance of genetic characteristics.  Analyzing genetic probabilities and risks in populations and families.  Plant and animal breeding.  Genetically modified organisms.

Week 8.  Linkage, sex-linkage and paternity.  How the organization of genes on chromosomes affects their inheritance.

Week 9.  Heritability.  How the effects of genes are identified and what can be learned from this analysis.

Week 10.  Lots more cool stuff we now can consider.  Mitochondrial genes and mutations, genetic mosaicism, fetal DNA in mothers, epigenetic inheritance, and other topics students may suggest.

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