Sleep: Neurobiology, Medicine, and Society

开始时间: 04/22/2022 持续时间: 9 weeks

所在平台: CourseraArchive

课程类别: 医学

大学或机构: University of Michigan(美国密歇根大学)

授课老师: Helen Baghdoyan Ralph Lydic



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The objective of this course is to give students the most up-to-the-date information on the biological, personal, and societal relevance of sleep. Personal relevance is emphasized by the fact that the single best predictor of daytime performance is the quality of the previous night's sleep. The brain actively generates sleep, and the first third of the course will overview the neurobiological basis of sleep cycle control. The course provides a cellular-level understanding of how sleep deprivation, jet lag, and substances such as alcohol, caffeine, and nicotine alter sleep and wakefulness. The second third of the course will cover sleep-dependent changes in physiology and sleep disorders medicine. Particular emphasis will be placed on disorders of excessive sleepiness, insomnia, and sleep-dependent changes in autonomic control. Chronic sleep deprivation impairs immune function and may promote obesity. Deaths due to all causes are most frequent between 4:00 and 6:00 A.M., and the second portion of the class will highlight the relevance of sleep for preventive medicine. The societal relevance of sleep will be considered in the final portion of the class. In an increasingly complex and technologically oriented society, operator-error by one individual can have a disastrous negative impact on public health and safety. Fatigue-related performance decrements are known to have contributed as causal factors to nuclear power plant failures, transportation disasters, and medical errors.


Part I – Brain Basis of Sleep
Lecture 1: Overview of Sleep: Neurobiology, Medicine, and Society©
Lecture 2: Sleep Phenomenology and Physiology
Lecture 3: Sleep Neurobiology 1
Lecture 4: Sleep Neurobiology 2
Lecture 5: Circadian Rhythms and Sleep

Part II – Sleep Disorders Medicine
Lecture 6: Sleep Medicine Overview
Lecture 7: Sleep Disordered Breathing
Lecture 8: Pediatric Sleep
Lecture 9: Sleep States and Anesthetic States
Lecture 10: Insomnia
Lecture 11: Sleep and Psychiatric Disorders

Part III – Sleep and Society
Lecture 12: Sleepiness and Sleep Need
Lecture 13: Sleep and Genetics
Lecture 14: Sleep and Learning
Lecture 15: Sleep and Dreaming
Lecture 16: Sleep and the Law



Students who have successfully completed this course in-person have described it as a survey class on sleep that is team taught by experts.