Introduction to Genomic Technologies

开始时间: 04/22/2022 持续时间: 4 weeks

所在平台: CourseraArchive 课程类别: 其他类别 大学或机构: Johns Hopkins University(约翰•霍普金斯大学)

课程主页: https://www.coursera.org/course/genintro

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课程详情

This course introduces you to the basic biology of modern genomics and the experimental tools used to measure this biology. The course will introduce the Central Dogma of Molecular Biology and cover how next generation sequencing can be used to measure DNA, RNA, and epigenetics. The course will also give a brief introduction to the key concepts in computing and statistics that you will need to understand how data from next generation sequencing are generated and analyzed.

课程大纲

1. The Central Dogma of Molecular Biology
2. How next generation sequencing works
3. Applications of next generation sequencing to measure
• DNA
• RNA
• Epigenetics (e.g. DNA methylation)
4. Basic concepts in computing on next generation sequencing data
• What is an algorithm? 
• What is a data structure?
• How to share data? 
5. Basic concepts in statistics for next generation sequencing
• Types of variation (biological, technological)
• Experimental design
• Signal and noise

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