Bioinformatic Methods II

开始时间: 04/22/2022 持续时间: 6 weeks

所在平台: CourseraArchive 课程类别: 生物与生命科学 大学或机构: University of Toronto（多伦多大学） 授课老师： Nicholas James Provart

课程主页: https://www.coursera.org/course/bioinfomethods2

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课程详情

Large-scale biology projects such as the sequencing of the human genome and gene expression surveys using RNA-seq, microarrays and other technologies have created a wealth of data for biologists. However, the challenge facing scientists is analyzing and even accessing these data to extract useful information pertaining to the system being studied. This course focuses on employing existing bioinformatic resources – mainly web-based programs and databases – to access the wealth of data to answer questions relevant to the average biologist, and is highly hands-on.

Topics covered include multiple sequence alignments, phylogenetics, gene expression data analysis, and protein interaction networks, in two separate parts.

The first part, Bioinformatic Methods I, dealt with databases, Blast, multiple sequence alignments, phylogenetics, selection analysis and metagenomics.

This, the second part, Bioinformatic Methods II, will cover motif searching, protein-protein interactions, structural bioinformatics, gene expression data analysis, and cis-element predictions.

This pair of courses is useful to any student considering graduate school in the biological sciences, as well as students considering molecular medicine.

课程大纲

Bioinformatic Methods II
Week 7: Protein motifs
Week 8: Protein-protein interactions
Week 9: Protein structure
Week 10: Gene expression analysis I
Week 11: Gene expression analysis II
Week 12: Cis regulatory elements             

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