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所在平台: CourseraArchive 课程类别: 健康与社会 大学或机构: University of Minnesota（美国明尼苏达大学） 授课老师： Matt McGue |
课程主页: https://www.coursera.org/course/behavioralgenetics
课程评论：没有评论
Behavioral genetic methodologies from twin and adoption studies through DNA analysis will be described and applied to address longstanding questions about the origins of individual differences in behavioral traits.
Unit #1: Introduction and Overview
Topics covered:
Unit #2: How Twins Saved Psychology
Topics covered:
Unit #3: Heritability, a Much Maligned and Misunderstood Concept
Topics covered:
A short primer on statistical (biometrical) genetics, how is heritability estimated?, what heritability is and what it is not, the shared versus the non-shared environment, gene-environment interaction.
Unit #4: What Everyone Should Know About the Human Genome
Topics covered:
What is a gene?, three surprising findings from the human genome project, the nature of genetic variation, genetic regulation and epigenetics, Prader-Willi & Angelman syndromes, Williams syndrome.
Unit #5: Schizophrenia: The Genetic Approach to a Psychiatric Phenotype
Topics covered:
What is schizophrenia?; twin and adoption studies – establishing a heritable basis; Identifying schizophrenia risk alleles - limits of the positional cloning strategy, what we have learned through GWAS, and the role of rare variants.
Unit #6: Behavioral Genetic Approaches to the Study of Intelligence
Topics covered:
What do psychologists mean by intelligence?, twin and adoption studies – establishing a genetic basis, identifying genes that influence individual differences in intelligence, genetics and intellectual disability.
Unit #7: Genetics and Behavioral Development
Topics covered:
Family socialization: a behavioral genetic perspective, the changing profile of genetic and environmental influences across development, gene-environment correlation: experience is not random, gene-environment interaction, genetics and aging.
Unit #8: Pulling It All Together: Summary, Public Policy, and Prospects
Topics covered:
The four laws of behavioral genetics, Huntington disease and the prospect of genetic counseling, individualized genomic medicine for behavioral disorders?, behavioral genetics and the courts, the future of behavioral genetics.
One of psychology’s defining issues concerns the origins of individual differences in behavior: Why are some people outgoing and cheerful while others are withdrawn and forlorn? Why do some struggle academically while others excel at school despite minimal study? Why do some suffer the ravages of a psychotic illness like schizophrenia while others enjoy a life free of mental illness? At the core to answering these questions is the ages-old "nature-nurture" debate: Are the behavioral differences among us due predominantly to inborn natural differences or the cumulative impact of our experiences? The nature-nurture debate generated much controversy and acrimony within psychology, although today most are willing to retire the debate and declare both sides victorious.
This course provides an introduction to behavioral genetics, the field within psychology that demonstrated that Nature and Nurture both play a fundamental role in the development of psychological traits. We will explore how early behavioral genetic research radically changed how psychologists conceptualized human behavior and how the mapping of the human genome is fundamentally altering current research approaches to a wide range of behavioral characteristics. The course will cover the traditional behavioral genetic methodologies of twin and adoption studies as well as modern approaches based on molecular genetic techniques.
Upon completion of the course, students should have a basic understanding of
