Survival Analysis in R for Public Health

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课程主页: https://www.coursera.org/archive/survival-analysis-r-public-health

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The Kaplan-Meier Plot
The Cox Model
The Multiple Cox Model
The Proportionality Assumption

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Welcome to Survival Analysis in R for Public Health! The three earlier courses in this series covered statistical thinking, correlation, linear regression and logistic regression. This one will show you how to run survival – or “time to event” – analysis, explaining what’s meant by familiar-sounding but deceptive terms like hazard and censoring, which have specific meanings in this context. Using the popular and completely free software R, you’ll learn how to take a data set from scratch, import it into R, run essential descriptive analyses to get to know the data’s features and quirks, and progress from Kaplan-Meier plots through to multiple Cox regression. You’ll use data simulated from real, messy patient-level data for patients admitted to hospital with heart failure and learn how to explore which factors predict their subsequent mortality. You’ll learn how to test model assumptions and fit to the data and some simple tricks to get round common problems that real public health data have. There will be mini-quizzes on the videos and the R exercises with feedback along the way to check your understanding. Prerequisites Some formulae are given to aid understanding, but this is not one of those courses where you need a mathematics degree to follow it. You will need basic numeracy (for example, we will not use calculus) and familiarity with graphical and tabular ways of presenting results. The three previous courses in the series explained concepts such as hypothesis testing, p values, confidence intervals, correlation and regression and showed how to install R and run basic commands. In this course, we will recap all these core ideas in brief, but if you are unfamiliar with them, then you may prefer to take the first course in particular, Statistical Thinking in Public Health, and perhaps also the second, on linear regression, before embarking on this one.

R的公共卫生生存分析:欢迎使用R的公共卫生生存分析! 本系列中的前三门课程涵盖统计思维,相关性,线性回归和逻辑回归。本教程将向您展示如何进行生存分析(或“事件发生的时间”)分析,并解释听起来熟悉但具有欺骗性的术语(例如危险和审查)的含义,这些术语在这种情况下具有特定含义。使用流行且完全免费的软件R,您将学习如何从头开始获取数据集,将其导入R,运行必要的描述性分析以了解数据的特征和怪癖,以及从Kaplan-Meier绘图到多重Cox回归。您将使用真实的,混乱的患者水平数据模拟的数据,用于因心力衰竭入院的患者,并了解如何探索哪些因素可以预测其后续死亡率。您将学习如何测试模型假设并适应数据,以及一些简单的技巧来解决真实的公共卫生数据所存在的常见问题。视频和R练习中将进行迷你测验,并附带反馈以检查您的理解。 先决条件 给出了一些公式以帮助理解,但这不是您需要数学学位来学习的课程之一。您将需要基本的计算能力(例如,我们不会使用微积分),并且需要熟悉显示结果的图形和表格方式。该系列的前三门课程介绍了假设检验,p值,置信区间,相关性和回归等概念,并介绍了如何安装R和运行基本命令。在本课程中,我们将简要回顾所有这些核心思想,但是如果您不熟悉它们,那么您可能更愿意参加第一门课程,特别是《公共卫生中的统计思维》,而第二门课程则是线性回归,在开始这个之前。

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