Genomics: Decoding the Universal Language of Life

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University of Illinois at Urbana-Champaign

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Genes, genomes, DNA: these words have slipped into our daily news cycles and our awareness, but what they actually mean often remains unclear. In these lessons, we aim to give you, not just the Biology 101 explanation of what a genome is, but a real-life perspective on why you already care about genomics – perhaps in ways you didn’t even realize. Are you interested in where your food comes from, what health conditions you are most likely to develop, what fish will share your aquarium most successfully? Genomes are a key to finding a better answer to these and other everyday questions.

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What is a genome? A genome contains all of the information that a cell needs to develop, function, and reproduce itself, and all the information needed for those cells to come together to form a person, plant, or animal. Genomes contain an organism’s complete set of genes, and also the even tinier genetic structures that help regulate when and how those genes are used. The ability to regrow a torn ligament, the clues that might predict the onset of mental illness, the nutritional potential of crops, and even the history of life itself, are all encoded in genomes. By taking this course, you will discover how scientists are deciphering the language of genomes to learn how to develop sustainable food and fuel supplies, improve disease treatment and prevention, and protect our environment. Professor Robinson is the main instructor for this course. In addition, each module features several guest instructors. These guest instructors come from diverse fields of study—biology, physics, computer science, and many others—and pursue diverse research goals, yet they share a common interest in genomic approaches and technologies. The guest instructors include: - Elizabeth (Lisa) Ainsworth, Associate Professor of Plant Biology - Mark Band, Director of the Functional Genomics Facility - Alison Bell, Associate Professor of Animal Biology - Jenny Drnevich, Functional Genomics Bioinformatics Specialist with High-Performance Biological Computing - Christopher Fields, Associate Director of High-Performance Biological Computing - Bruce Fouke, Director of the Roy J. Carver Biotechnology Center - Glenn Fried, Director of the Carl R. Woese Institute for Genomic Biology Core Facilities - Nigel Goldenfeld, Professor of Physics - Brendan Harley, Assistant Professor of Chemical and Biomolecular Engineering - Alvaro Hernandez, Director of the High-Throughput Sequencing and Genotyping Facility - Victor Jongeneel, former NCSA Director of Bioinformatics and former Director of High-Performance Biological Computing - Kingsley Boateng, Senior Research Specialist with the Carl R. Woese Institute for Genomic Biology Core Facilities - Stephen Long, Professor of Plant Biology and Crop Sciences - Ruby Mendenhall, Associate Professor of African American Studies - William Metcalf, Professor of Microbiology - Karen Sears, Assistant Professor of Animal Biology - Saurabh Sinha, Associate Professor of Computer Science - Lisa Stubbs, Professor of Cell and Developmental Biology - Rachel Whitaker, Associate Professor of Microbiology - Derek Wildman, Professor of Molecular and Integrative Physiology - Peter Yau, Director of the Protein Sciences Facility

基因组学:解读生命的通用语言:什么是基因组?基因组包含细胞发展,功能和自我复制所需的所有信息,以及这些细胞聚集在一起以形成人,植物或动物所需的所有信息。基因组包含有机体的完整基因集,以及甚至更细小的遗传结构,有助于调节何时以及如何使用这些基因。 韧带撕裂的再生能力,可能预测精神疾病发作的线索,农作物的营养潜力以及生命本身的历史都被编码在基因组中。通过学习本课程,您将发现科学家如何解读基因组的语言,以学习如何开发可持续的食品和燃料供应,改善疾病的治疗和预防以及保护我们的环境。 罗宾逊教授是该课程的主要讲师。此外,每个模块都配备了数位客座讲师。这些客座讲师来自不同的研究领域(生物学,物理学,计算机科学等),追求着不同的研究目标,但他们对基因组方法和技术有着共同的兴趣。客座讲师包括: -伊丽莎白(Lisa)Ainsworth,植物生物学副教授 -功能基因组学研究所所长Mark Band -动物生物学副教授艾莉森·贝尔(Alison Bell) -高性能生物学计算的功能基因组学生物信息学专家Jenny Drnevich -克里斯托弗·菲尔德斯(Christopher Fields),高性能生物计算副主任 -Roy J. Carver生物技术中心主任Bruce Fouke -卡尔·沃斯基因组生物学核心设施研究所所长Glenn Fried -Nigel Goldenfeld,物理学教授 -Brendan Harley,化学与生物分子工程学助理教授 -高通量测序和基因分型设备主管Alvaro Hernandez -Victor Jongeneel,前NCSA生物信息学主任和高性能生物计算主任 -金斯利·博阿滕(Kingsley Boateng),卡尔·R·沃斯(Carl R. Woese)基因组生物学核心设施研究所高级研究专家 -Stephen Long,植物生物学与作物科学教授 -非裔美国人研究副教授Ruby Mendenhall -William Metcalf,微生物学教授 -Karen Sears,动物生物学助理教授 -Saurabh Sinha,计算机科学副教授 -Lisa Stubbs,细胞与发育生物学教授 -Rachel Whitaker,微生物学副教授 -Derek Wildman,分子与整合生理学教授 -蛋白质科学机构主任丘耀

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