Drug Discovery

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University of California, San Diego

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This week we will be hearing from Phillip Bourne, PhD. Dr. Bourne was, at the time of this recording, the Associate Vice Chancellor for Innovation and Industrial Alliances in the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. Since that time, he has been named the first Associate Director for Data Science at the United States National Institutes of Health.

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The University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences Drug Discovery course brings you lectures from both faculty and industry experts. With this course, recorded on campus at UCSD, we seek to share our access to top people in the field who bring an unprecedented range of expertise on drug discovery. In this course you will learn the drug discovery process up to the filing of an Initial New Drug Application or IND. Each week you will learn the steps that a pharmaceutical or biotech company goes through to discover a new therapeutic drug. In this course you will be able to: * Understand the pharmaceutical and biotechnology market a changing landscape * Learn the major aspects of the drug discovery process, starting with target selection, to compound screening to designing lead candidates. * Recognize current modern drug discovery based on the lock-and-key theory, which attempts to use one single compound to hit one target to combat the related disease. * Increase understanding of the various drug discovery tools and methods that are used for finding, identifying and designing a new drug. * Define and understand the regulatory responsibilities for drug discovery to file an Investigational New Drug Application (IND). This course is intended as part 1 of a series: Drug Discovery, Drug Development (https://www.coursera.org/learn/drug-development) and Drug Commercialization (https://www.coursera.org/learn/drug-commercialization). We would highly recommend that you take the courses in order since it will give you a better understanding on how a drug is discovered in the lab before being tested in clinical trials and then launched in the market place.

药物发现:加利福尼亚大学圣地亚哥分校斯卡格斯药学院和药物科学学院药物发现课程为您带来了来自教师和行业专家的演讲。通过本课程,该课程记录在UCSD的校园中,我们力求与那些在药物发现领域拥有空前专业知识的顶尖人才分享我们的访问机会。 在本课程中,您将学习药物发现过程,直至提交初始新药申请或IND。每周您将学习制药公司或生物技术公司发现新治疗药物的步骤。在此课程中,您将能够:   *了解制药和生物技术市场的变化趋势   *了解药物发现过程的主要方面,从目标选择开始,从化合物筛选到设计潜在候选人。   *基于锁定和钥匙理论来认识当前的现代药物发现,该理论试图使用一种单一的化合物击中一个目标来对抗相关疾病。   *增进对用于发现,识别和设计新药物的各种药物发现工具和方法的了解。   *定义并了解药品发现的监管责任,以提交新药研究申请(IND)。 本课程是本系列的第1部分:药物发现,药物开发(https://www.coursera.org/learn/drug-development)和药物商业化(https://www.coursera.org/learn/drug -商业化)。我们强烈建议您按顺序学习这些课程,因为这样可以使您更好地了解在临床试验中测试药物然后在市场上投放之前如何在实验室发现药物。

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