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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/synbioethics
课程评论：没有评论
课程名称：工程生活：合成生物学、生物伦理与公共政策 课程概述：合成生物学（Synbio）是一个涵盖多种应用的多样领域，不同的背景（例如，功能获得研究、生物燃料）带来了不同的伦理和治理挑战。该课程的目标是提高学习者对合成生物学设计、实施和应用中出现的伦理以及政策/治理问题的认识和理解。课程将首先介绍重组DNA技术的简短历史，以及这一科学治理如何发展和演变，接着深入探讨合成生物学的各个应用领域。 内容将以多种形式呈现，包括阅读材料、讲座、以及与科学家、伦理学家和政策制定者的录制和现场访谈及讨论。学习者将有机会思考、撰写和讨论他们在自己工作中的问题与挑战，以及现实案例中的相关事宜。最后一个项目将使学生参与到合成生物学治理模型的开发中。 课程大纲： 1. **欢迎来到工程生活：合成生物学、生物伦理与公共政策** 2. **重组DNA技术：科学与历史** - 学习重组DNA技术的发展历史及其引发的伦理和政策问题。 - 包括讲座视频、阅读材料以及与LeRoy Walters的访谈。 - 结束时有测验。 3. **功能获得研究（GOF）** - 讨论合成生物学中功能获得研究及其引发的双用途担忧。 - 包括讲座视频、外部视频和阅读材料。 - 进行首次同行评估项目，聚焦于GOF研究政策相关的伦理责任。 4. **生物燃料** - 学习生物燃料及其所引发的复杂伦理问题，以及合成生物学在生物燃料开发中的角色。 - 包括讲座视频、外部视频、阅读和与Deborah Scott的访谈。 - 结束时有测验。 5. **人类健康** - 了解合成生物学在人类健康中的应用及人类受试者研究的伦理问题。 - 包括讲座视频、外部视频和阅读材料。 - 进行第二次同行评估项目，专注于政策决策中的利益相关者与决策者的伦理责任。 6. **治理** - 讨论新兴生物技术的治理模型及公众参与在科学发展与监督中的作用。 - 包括讲座视频、外部视频和阅读材料，以及与LeRoy Walters和Jane Calvert的访谈。 - 最后项目要求学员发展并辩护一项与转基因蚊子释放相关的政府政策的决策过程。
Name:Welcome to Engineering Life: SynBio, Bioethics & Public Policy
Description:
Name:Recombinant DNA Technology: Science and History
Description:We start the course by learning a bit about the history and context of the development of recombinant DNA (rDNA) technology in the 1970s, the ethics and policy issues raised by that science, and how those issues remain with us today in synthetic biology. The work of the week includes lecture videos, readings, and an interview with LeRoy Walters, who was involved in the discussions and debates about rDNA in its early years. The week will conclude with a quiz.
Name:GOF Research
Description:In Week 2 we will learn about and discuss gain of function (GOF) research and the dual-use concerns raised by synthetic biology. The work of the week includes lecture videos, a number of outside videos, and readings. The assessment this week will be your first peer-assessed project, and will focus on identifying ethical duties related to GOF research policy.
Name:Biofuels
Description:This week, we’ll learn about biofuels, the complex task of balancing the many ethical issues they raise, and the role of synthetic biology in biofuels development. The work of the week includes lecture videos, one outside video, readings, and an interview with Deborah Scott about biofuels governance. The week will conclude with a quiz.
Name:Human Health
Description:This week we will learn a bit about applications of synthetic biology to human health, and the ethics of human subjects research. The work of the week includes lecture videos, one outside video, and readings. The assessment this week will be your second peer-assessed project, and will build on your first project, from Week 2. This project will focus on identifying stakeholders in a policy decision, their interests in the decision, and the related ethical duties of the decision-maker.
Name:Governance
Description:In the final week of the course, we will talk about both models of governance for emerging biotechnologies and the role of public engagement in the development and oversight of the science. The work of the week includes lecture videos, one outside video, and readings, as well as interviews with LeRoy Walters and Jane Calvert. The final course project builds on the Week 2 and 4 peer-assessed projects, and goes a step further, asking you to develop and defend a decision-making process for a government policy related to the release of genetically modified mosquitoes.
Synbio is a diverse field with diverse applications, and the different contexts (e.g., gain-of-function research, biofuels) raise different ethical and governance challenges. The objective of this course is to increase learners’ awareness and understanding of ethical and policy/governance issues that arise in the design, conduct and application of synthetic biology. The course will begin with a short history of recombinant DNA technology and how governance of that science developed and evolved, and progress through a series of areas of application of synbio. Content will be presented in many forms, including not only reading and lectures, but also recorded and live interviews and discussions with scientists, ethicists and policy makers. Learners will have the opportunity to think, write and talk about the issues and challenges in their own work and in real-life case examples. A final project will engage students in the development of governance models for synbio.
