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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/stem-cells
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课程名称：干细胞科学 课程概述：干细胞对于治疗各种医疗条件承载着怎样的希望？在这门为期五部分的在线课程中，您将探索干细胞的历史和基本生物学，了解新研究技术，并发现干细胞如何可能带来疾病的治愈和个性化医疗。您将听取博物馆科学家、处于前沿领域的医学研究人员以及一组生物伦理学专家的讲解，他们将讨论干细胞研究和治疗的伦理影响。通过学习，您将了解已有的成就、仍然存在的挑战以及未来可能出现的医学突破。 课程大纲： 1. **干细胞简介** - 欢迎来到干细胞科学课程！您将从干细胞的基本概述开始，了解干细胞是什么、干细胞研究的发展历史以及其潜在的治疗应用。AMNH生物学家朱莉亚·齐切洛将分享干细胞在生命树中的分布。 2. **干细胞如何工作？** - 本周，纽约大学的埃斯特班·马佐尼博士将讨论科学家如何引导干细胞分化为特定细胞类型。他还将谈论诸如线粒体替代疗法和用于器官移植的嵌合体生成等新兴的干细胞辅助技术。同时，您将了解到克隆的科学和伦理背景。 3. **利用干细胞研究疾病** - 在这一部分，您将了解科学家如何利用细胞培养模型来研究疾病。哥伦比亚大学的安德鲁·斯普劳尔博士将解释如何使用培养的细胞理解疾病的成因，并寻求潜在的治疗药物。他的研究重点是阿尔茨海默病。此外，您还将探索干细胞在糖尿病研究中的潜在应用。 4. **利用干细胞治疗疾病** - 除了在疾病研究中的潜力外，干细胞还能够用于实际治疗疾病。神经干细胞开创者萨莉·坦普尔博士将解释如何利用我们自己身体内的干细胞（成人干细胞）治疗与年龄相关的黄斑变性，这是一种日益常见且致残的疾病。她还会为您提供评估潜在干细胞治疗的工具。 5. **干细胞研究及治疗的生物伦理学** - 在课程结束时，一组生物伦理学专家将讨论围绕人类胚胎干细胞的一些争议以及与干细胞在基础和临床研究中应用相关的法律、政策和伦理挑战。您将有机会讨论和提问有关生殖技术和干细胞研究的未来。 通过此课程，学员将深入了解干细胞的科学基础、应用潜力以及相关的伦理问题，为未来的科研和医学进步提供更全面的视野。
Name:Introduction to Stem Cells
Description:Welcome to The Science of Stem Cells! You will begin with a basic overview of stem cells--what they are, the history of stem cell research, and the potential for stem cell therapies. You will also learn from AMNH biologist Julia Zichello that stem cells are found throughout the tree of life.
Name:How Do Stem Cells Work?
Description:This week, New York University’s Dr. Esteban Mazzoni will discuss how scientists can coax stem cells to differentiate into particular cell types. Dr. Mazzoni will also talk about new stem cell-assisted technologies such as mitochondrial replacement therapy and generating chimeras for organ transplantation. You will also get some background information on the science and ethics of cloning.
Name:Using Stem Cells to Study Disease
Description:We have covered the process by which scientists can differentiate cells in a culture dish. Now you will look at how scientists can use these cell to model diseases in a culture dish. Dr. Andrew Sproul from Columbia University explains how cultured cells can be used to understand the cause of diseases and to look for drugs that will potentially cure them. His research is on Alzheimer’s disease. You will also explore how how stem cells have the potential to help with the study of diabetes.
Name:Using Stem Cells to Treat Disease
Description:In addition to the great potential of stem cells to be used in the study of disease, stem cells can also be used to actually treat disease. Neural stem cell pioneer Dr. Sally Temple will explain the potential for using stem cells in our own bodies (adult stem cells) to treat age-related macular degeneration, an increasingly common and debilitating disease. Dr. Temple will also give you some tools for evaluating potential stem cell treatments.
Name:The Bioethics of Stem Cell Research and Therapy
Description:To complete the course, a panel of bioethics experts will discuss some of the controversies surrounding human embryonic stem cells and the legal, policy, and ethical challenges associated with the use of stem cells in basic and clinical research. You will have an opportunity to discuss and ask questions about the future of reproductive technology and stem cell research.
What promise do stem cells hold for the treatment of medical conditions? In this five-part online course you will explore the history and basic biology of stem cells, learn about new research techniques, and find out how stem cells could lead to cures for diseases and to individualized medicine. You will hear from Museum scientists, medical researchers at the frontiers of the field, and a panel of bioethics experts who will address the ethical implications of stem cell research and therapy. Learn what has already been accomplished, what challenges remain, and what medical breakthroughs may lie ahead.
