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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/medical-applications-particle-accelerators
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课程简介：粒子加速器的医学应用（NPAP MOOC） 欢迎参加本课程！NPAP——粒子加速器医学应用课程是北欧粒子加速器项目（NPAP）中的三门课程之一。本课程将带您探索粒子加速器在医学领域的应用，重点介绍两种重要但不同的应用：肿瘤的放射治疗和用于诊断及治疗的医学同位素的生产。课程共有四个模块，涵盖以上内容。 第一模块介绍了放射治疗的基本原理，从医学和物理学的角度出发。您将了解用于放射治疗的机器的主要组成部分，以及放射治疗在癌症治疗中的重要性。 第二模块将引导您了解放射治疗中使用的不同类型的线性加速器，同时描述治疗头的设计。治疗头的设计至关重要，因为它决定了剂量和照射区域。患者接受的剂量也是在治疗头中进行测量的。 在第三模块中，您将接触到质子治疗。这种治疗方法首先加速质子，然后通过磁铁引导其到达肿瘤。这些机器通常比用于放射治疗的机器要大得多且昂贵。本模块还将提供不同类型加速器的描述和比较，并解释质子如何与组织相互作用。 第四模块介绍了比质子重的离子在癌症治疗中的应用，并引入了医学同位素的生产。您将了解到同位素是如何在质子和离子加速器中生产的，以及它们在医院中不同用途的角色。例如，医学同位素常用于正电子发射断层扫描（PET）。 尽情享受这门课程吧！
Name:Introduction to the course and radiotherapy
Description:Welcome to this course on medical applications of accelerators. The most important applications of accelerators in medicine are radiotherapy and diagnostic imaging using radionuclides, which both play a very important role in the treatment of cancer. Thus, the course focuses on these two applications of accelerators in medicine. In fact, accelerators for radiotherapy is the largest application of accelerators altogether with more than 11000 accelerators worldwide. These accelerators range from very compact electron linear accelerators with a length of only about 1 m to large carbon ion synchrotrons with a circumference of more than 50 m and a huge rotating carbon ion gantry with a weight of 600 tons. The course starts with an introduction to radiotherapy with focus on the biological properties of ionizing radiation. Subsequently, the electron linac for radiotherapy is presented. The main components of the electron linac are the multi-energy linac structure and the treatment head, which converts the electron beam to the desired dose distribution in the patient. Next, proton accelerators for radiotherapy are discussed with focus on the applied accelerator types and the treatment delivery technologies. Treatment with heavy ions and the challenges of proton and heavy ion therapy are also presented. Finally, the medical application of radionuclides are introduced and the production of radionuclides with cyclotrons is discussed.
Name:Electron linacs for radiotherapy
Description:
Name:Proton therapy I
Description:
Name:Proton therapy II and production of medical radionuclides
Description:
Hello and welcome to this course! The NPAP - Medical Applications of Accelerators is one out of three courses in the Nordic Particle Accelerator Program (NPAP). Here you will be taken on a tour focusing on the medical applications of particle accelerators. You will see that there are two very important, but different, applications of accelerators in hospitals. The first application concerns radiotherapy of tumours and the other concerns the production of medical nuclides for diagnosis and treatment. Both will be included in this course and described through four modules. The first module offers the basic principles of radiotherapy from a medical and physics point of view. You there learn about the main components of the machines used for radiotherapy and get to know why radiotherapy is important for cancer treatments. The second module guides you through the different types of linear accelerators used in the machines for radiotherapy. It also describes the design of the treatment head. The design is important because it is the settings of the treatment head that determines the dose and the radiated region. It is also in the treatment head where the dose given to the patient is measured. In the third module you are introduced to proton therapy. In this type of therapy protons are first accelerated and then guided down to the tumour by magnets. The machines are considerably larger and more expensive than machines used for radio therapy. The module also offers a description and comparison between different types of accelerators, and explains how the protons interact with tissue. Also ions that are heavier than protons can be used in cancer therapy. This is described in the fourth module, where we also introduce you to the production of medical nuclides. You learn how the nuclides are produces in proton and ion accelerators and how the nuclides come into play at different places in hospitals. Medical nuclides are for instance used in Positron Electron Tomography, PET. Enjoy!
