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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/introduction-genomics
课程评论：没有评论
课程名称：基因组技术导论 课程概述：本课程将带您了解现代基因组学的基本生物学以及我们用来测量基因组的实验工具。我们将介绍分子生物学的中心法则，并探讨如何利用下一代测序技术测量DNA、RNA和表观遗传模式。此外，您还将接触到计算和数据科学的关键概念，以帮助您理解下一代测序实验中数据的生成和分析。此课程为基因组数据科学专业的第一门课程。 课程大纲： 第一部分：概述 描述：在这一模块中，您将学习“足够的分子生物学知识”，“基因组”，“撰写DNA序列”，“中心法则”，“转录”，“翻译”和“DNA结构与修饰”等主题。 第二部分：测量技术 描述：在此模块中，您将了解聚合酶链反应、下一代测序以及测序的应用。 第三部分：计算技术 描述：本模块的讲座将涵盖计算技术的一些基本主题。我们将讨论计算机科学的基础、算法、内存和数据结构、效率、软件工程以及计算生物学软件。 第四部分：数据科学技术 描述：在此模块中，我们将讨论如何处理测序过程中产生的数据。内容包括可重复性、分析、统计、问题类型、推断的中心法则、分析代码、测试、预测、变异、实验设计、混淆、效能、样本量、相关性、因果关系和自由度等多个方面的信息。
Part: 1
Title:Overview
Description:In this Module, you can expect to study topics of "Just enough molecular biology", "The genome", "Writing a DNA sequence", "Central dogma", "Transcription", "Translation", and "DNA structure and modifications".
Part: 2
Title:Measurement Technology
Description:In this module, you'll learn about polymerase chain reaction, next generation sequencing, and applications of sequencing.
Part: 3
Title:Computing Technology
Description:The lectures for this module cover a few basic topics in computing technology. We'll go over the foundations of computer science, algorithms, memory and data structures, efficiency, software engineering, and computational biology software.
Part: 4
Title:Data Science Technology
Description:In this module on Data Science Technology, we'll be covering quite a lot of information about how to handle the data produced during the sequencing process. We'll cover reproducibility, analysis, statistics, question types, the central dogma of inference, analysis code, testing, prediction, variation, experimental design, confounding, power, sample size, correlation, causation, and degrees of freedom.
This course introduces you to the basic biology of modern genomics and the experimental tools that we use to measure it. We'll introduce the Central Dogma of Molecular Biology and cover how next-generation sequencing can be used to measure DNA, RNA, and epigenetic patterns. You'll also get an introduction to the key concepts in computing and data science that you'll need to understand how data from next-generation sequencing experiments are generated and analyzed. This is the first course in the Genomic Data Science Specialization.
