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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/immunologyfundamentalstcellssignaling
课程评论：没有评论
课程名称：免疫学基础：T细胞与信号传导 课程概述：这是名为“免疫学基础”系列课程中的第二门课程，总共包含三门课程。每门课程的内容都建立在之前课程的基础上。本课程是对身体保持健康所使用的防御机制的后半部分的学习。第一部分我们学习了先天免疫和B细胞功能，第二部分则重点讲述T细胞功能及免疫应答的协调。 本课程进一步探讨了补体的功能、MHC蛋白向T细胞的呈递、T细胞的发展和信号传导。早期的讲座使用隐喻、卡通和模型来帮助理解和记忆细胞、组织和器官的相关知识。课程内容包括MHC蛋白和T细胞受体的结构及其变异来源，配合基因重排、发育过程和信号级联的动画展示。测试环节采用多项选择题，涉及事实、概念和原理应用，可能会引用讲座中使用的图表、绘图和照片，并在大纲中重现。 学习内容： - 补体如何利用适应性和先天性触发机制来靶向病原体。 - MHC蛋白的详细结构与编码，以及α-β和γ-δ受体的功能及其如何相互作用以启动适应性免疫应答。 - 信号传导的基础知识及外部接收和内部激活通路的多样性。 - 理解信号和交叉谈话如何控制免疫系统的活动。 课程大纲： - 补体 - 主要组织相容性复合体（MHC） - 抗原处理与呈递 - T细胞受体 - T细胞发展 - 细胞因子与信号传导 - 期末考试 该课程为参与者提供了深入了解T细胞在免疫反应中的作用及其信号传导过程的机会，有助于提升对免疫系统复杂性和交互作用的认识。
Name:Complement
Description:
Name:The Major Histocompatability Complex
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Name:Antigen Processing and Presentation
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Name:T-Cell Receptors
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Name:T-Cell Development
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Name:Cytokines and Signaling
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Name:Final
Description:
Course 2 of a three course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material. This is the second half of the journey through the defenses your body uses to keep you healthy. In the first part we learned about innate immunity and B cell function. The second part covers T cell function and coordination of the immune response. Fundamentals of Immunology: T cells and Signaling builds on the first course to describe the functions of Complement, MHC presentation to T cells, T cell development and signaling. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. This course includes the structure of both MHC proteins and T cell receptors and the sources of variation. The course provides animations of gene rearrangement, developmental processes and signal cascades. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline. What You’ll Learn: How complement uses adaptive and innate triggers to target pathogens. The detailed structure and coding of MHC proteins and both alpha-beta and gamma delta receptors and how these proteins interact to initiate an adaptive immune response. The basics of signaling, and the varieties of external receipt and internal activation pathways. We bine the process of putting together how signals and crosstalk control the activity of the immune system.
