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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/immunology-immune-system-and-infectious-diseases
课程评论：没有评论
课程名称：免疫学：免疫系统与传染病 课程概述：人类免疫系统与病原体之间的斗争对我们的健康构成了数千年来的重大威胁。传染病仍然是全球主要的死亡原因，通常由细菌（胞内和胞外）、病毒、真菌、寄生虫（虫类/蠕虫）和朊病毒引起。在正常情况下，免疫反应通过分子和细胞机制对这些病原体提供强有力的防护。 课程大纲： 1. **针对细菌的免疫反应** 本模块将探讨人类宿主针对细菌感染的先天性和获得性防御机制。内容将涉及对胞内和胞外细菌的不同反应，特别是参与保护的特定细胞亚群及其所使用的分子和机制。 2. **病毒免疫与逃逸机制** 本模块将研究人类宿主针对病毒感染的先天性和获得性防御机制。内容包括参与保护的特定细胞和分子免疫机制，以及病毒为逃避免疫系统而发展出的一系列策略，案例包括SARS-CoV-2病毒。 3. **针对真菌感染的免疫反应** 本模块深入探讨哺乳动物宿主对这种真核病原体所采取的免疫机制，讨论参与响应的特定细胞和分子，通过具体示例了解免疫系统如何回应宿主遇到的各种真菌。 4. **对利什曼病寄生虫的免疫反应** 本模块将探索对这种被忽视的寄生虫感染的先天性和获得性免疫反应，分析特定细胞和分子的相互作用，并讨论寄生虫如何利用免疫系统规避破坏。 5. **疟疾感染与免疫反应** 本模块将研究我们对这一致命寄生虫的免疫反应，专家将讲解参与反应的细胞和分子，以及寄生虫生命周期各个阶段所采取的免疫反应的不同阶段，同时探讨对临床症状的免疫抵抗及在有效预防和治疗方法开发中遇到的困难。 6. **结核病与人类免疫** 本模块聚焦于对结核病的理解，讲师将介绍这种由单一病原体引起的全球死亡原因的多样性症状，探索我们对该病原体的免疫反应、结核病流行的影响因素和免疫病理学。 总体来看，本课程将帮助学习者深入理解免疫系统如何应对各种传染病，以及这些疾病对全球健康的影响。
Name:Immune response to bacteria
Description:In module one, you will explore the innate and adaptive mechanisms of defence against bacterial infections in the human host. As they differ, the responses to both intracellular and extracellular bacteria will be discussed. In particular, you will learn about the specific cell subsets that are involved and the molecules and mechanisms they deploy to provide protection against these pathogenic infections.
Name:Viral immunity and evasion
Description:In module two, we will explore both innate and adaptive mechanisms of defence against viral infections in the human host. The specific cellular and molecular immune mechanisms involved in this protection will be discussed. Finally, our experts will explain the plethora of strategies developed by the viruses to evade from our immune system and that ultimately allow them to survive and sometimes thrive in their mammalian host. Some examples will be discussed, including SARS-CoV-2.
Name:Immunity against fungal infections
Description:Module three of this course will explore in detail the immune mechanisms deployed by the mammalian host to combat this particular eukaryotic type of pathogen. In particular, you will discuss the role of specific cells and molecules involved and, using specific examples, you understand how our immune system responds to the various types of fungus its host encounters.
Name:Immune responses to Leishmania parasites
Description:In module four, you will explore the innate and adaptive immune responses to this neglected parasitic infection. The specific cells and molecules and their interactions will be explored. Using the different forms of the diseases, our expert will discuss how the parasite is able to use the immune system to evade destruction.
Name:Malaria infection and immunity
Description:Module five will investigate our immune response to this deadly parasite. Presented by our experts in the field, this module will cover the cells and molecules involved as well as the different phases of immune response deployed in the various phases of the parasite’s life cycle in the host. The module will also cover immune resistance to the clinical symptoms of the disease and will explain the difficulties encountered in the development of efficient prevention and treatment options.
Name:Tuberculosis and human immunity
Description:Module six, our last in the course, is dedicated to understanding tuberculosis. Led by our experts in the field, you will discover the symptomatic diversity of this bacterial infection, the primary cause of death worldwide resulting from a single pathogen. You will explore our immune response against this pathogen, the factors contributing to the ongoing tuberculosis epidemic and the immunopathology of the disease.
The constant struggle between pathogens and the human immune system has been posing a significant threat to our health for thousands of years. Infectious diseases remain the leading cause of death worldwide. These are typically caused by bacteria (intra- and extracellular), viruses, fungi, parasites (worms/helminths) and prions. Under normal circumstance, the immune response orchestrates a robust protection against these pathogens using both molecular and cellular mechanisms. This usually leads
