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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/immunology-friendlyfire
课程评论：没有评论
课程名称：免疫学基础：友谊之火的死亡 概述：该课程是“免疫学基础”专项的第三门课程，共有三门课程。每门课程的内容均在前一门课程的基础上进行扩展。这是了解我们身体如何使用防御机制保持健康的最后一段旅程。在第一门课程中，我们学习了先天免疫和B细胞功能；在第二门课程中，我们研究了T细胞功能和免疫应答的协调。 “免疫学基础：友谊之火的死亡”介绍了适应性免疫系统和先天性免疫系统的基本功能。早期讲座通过隐喻、卡通和模型来提高理解和记忆，涵盖细胞、组织和器官的相关知识。在描述抗体的形式、功能、起源及种类后，后续讲座详细讲解了变异生成的机制。本课程还提供了基因重排和类别转换的动画，以及与抗体结构的详细物理模型相关的亲和力成熟。最后一节讲座则在解剖背景下回顾这些概念。测试形式为选择题，考察事实、概念和原理应用，问题可能涉及讲座中使用的图表、绘图和照片，并在大纲中复制。 学习内容： - 免疫细胞的概述及其如何攻击病原体，重点讲解诱导细胞凋亡的机制和抗体介导的细胞毒性。 - 炎症反应及容忍机制的生成，顺序呈现以强调在控制攻击时的决策过程。 - 自身免疫疾病的概述，包括其特征、原因和治疗。 - 超敏反应的概述，包括过敏、过敏性休克、贫血、肉芽肿和多种皮肤反应，伴随识别、预防和治疗的内容。 - 最后讨论预防移植排斥反应，之前讲解抗体技术及不相容性检测的方法。 课程大纲： - 细胞免疫 - 炎症 - 容忍 - 自身免疫 - 超敏反应 - 移植免疫
Name:Cellular Immunity
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Name:Inflamation
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Name:Tolerance
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Name:Autoimmunity
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Name:Hypersensitivity
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Name:Transplant Immunity
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Course 3 of a three course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material. This is the third leg of the journey through the defenses your body uses to keep you healthy. In the first course we learned about innate immunity and B cell function. In the second course we studied T cell function and coordination of the immune response. Fundamentals of Immunology: Death by Friendly Fire introduces students to the basic functions of the adaptive and innate immune systems. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. After describing the form, function, origin and varieties of antibodies, subsequent lectures provide details on the mechanism of the generation of variation. The course provides animations of gene rearrangement and class switching and descriptions of affinity maturation correlated with detailed physical models of antibody structure. The final lecture reviews these concepts in anatomical context. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline. What You’ll Learn: A survey of immune cells and how they attack pathogens, with emphasis on the mechanism of inducing apoptosis and details of Antibody Directed Cell-mediated Cytotoxicity. The inflammatory response and mechanisms of generating tolerance, presented in sequence to emphasize the decision making involved in controlling attacks. A survey of autoimmune disease, their characteristics, cause and treatment. Survey of hypersensitivity reactions, including allergy, anaphylaxis, anemias, granulomas, and a variety of skin responses. This is accompanied by identification, prevention and treatment. The final discussion of preventing transplant rejection is preceded by a detailed unit on antibody technology and the methods of testing for incompatibility.
