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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/drug-discovery
课程评论：没有评论
课程名称：药物发现 概述：加州大学圣地亚哥分校斯卡格斯药学院的药物发现课程提供来自学术界和行业专家的讲座。该课程在UCSD校园内录制，旨在分享我们在药物发现领域访问顶尖人才的机会，这些专家在药物发现方面拥有前所未有的专业知识。在本课程中，您将学习药物发现的全过程，直到提交初始新药申请（IND）。每周，您将了解制药或生物技术公司在发现新治疗药物过程中所经历的步骤。 通过本课程，您将能够： - 理解制药和生物技术市场的变化。 - 学习药物发现过程的主要方面，从目标选择到化合物筛选，再到设计主导候选药物。 - 认识基于锁和钥匙理论的现代药物发现方法，该理论尝试使用单一化合物靶向一个特定目标以对抗相关疾病。 - 增加对用于发现、识别和设计新药的各种药物发现工具和方法的理解。 - 明确和理解药物发现的监管责任，以提交研究性新药申请（IND）。 本课程是一个系列的第一部分：药物发现、药物开发和药物商业化。我们强烈建议您按顺序参加这些课程，因为这样可以更好地理解药物如何在实验室被发现，随后进行临床试验并最终推向市场。 大纲： 1. 欢迎！ 2. 制药和生物技术行业概况 - 课程负责人Dr. Williams Ettouati介绍了制药和生物技术的全景概述。 3. 药物发现：蛋白质组学和基因组学 - Phillip Bourne博士分享相关内容。 4. 化合物选择与临床前研究 - Ronald Christopher博士介绍实验室工作。 5. 针对蛋白激酶的碎片基础药物发现挑战 - Stephen Burley博士对此主题进行讨论。 6. 药物传递的关键概念 - UCSD临床药学及儿科教授Brookie Best博士授课。
Name:Welcome!
Description:
Name:Pharmaceutical & Biotechnology Industry Landscape
Description:In this module course lead Dr. Williams Ettouati begins by giving a landscape overview of the Pharma and Biotechnology landscape.
Name:Drug Discovery: Proteomics, Genomics
Description:This week we will be hearing from Phillip Bourne, PhD. Dr. Bourne was, at the time of this recording, the Associate Vice Chancellor for Innovation and Industrial Alliances in the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. Since that time, he has been named the first Associate Director for Data Science at the United States National Institutes of Health.
Name:Compound Selection & Preclinical Studies
Description:This week we will hear from Ronald Christopher, Ph.D. Dr. Ronald Christopher, Vice President of Preclinical Trials at Arena Pharmaceuticals.
Name:Challenges in Fragment Based Drug Discovery for Protein Kinases
Description:In this module we will hear from Stephen Burley, M.D., Ph.D. At the time of this recording, Director of the Center for Integrative Proteomics at Rutgers University. He is now the Director of the Protein Data Bank and remains an Adjunct Professor at the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences.
Name:Key Concepts in Drug Delivery
Description:This module we hear from Professor of Clinical Pharmacy and Pediatrics, Brookie Best, Pharm. D., of UCSD's Skaggs School of Pharmacy and Pharmaceutical Sciences.
The University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences Drug Discovery course brings you lectures from both faculty and industry experts. With this course, recorded on campus at UCSD, we seek to share our access to top people in the field who bring an unprecedented range of expertise on drug discovery. In this course you will learn the drug discovery process up to the filing of an Initial New Drug Application or IND. Each week you will learn the steps that a pharmaceutical or biotech company goes through to discover a new therapeutic drug. In this course you will be able to: * Understand the pharmaceutical and biotechnology market a changing landscape * Learn the major aspects of the drug discovery process, starting with target selection, to compound screening to designing lead candidates. * Recognize current modern drug discovery based on the lock-and-key theory, which attempts to use one single compound to hit one target to combat the related disease. * Increase understanding of the various drug discovery tools and methods that are used for finding, identifying and designing a new drug. * Define and understand the regulatory responsibilities for drug discovery to file an Investigational New Drug Application (IND). This course is intended as part 1 of a series: Drug Discovery, Drug Development (https://www.coursera.org/learn/drug-development) and Drug Commercialization (https://www.coursera.org/learn/drug-commercialization). We would highly recommend that you take the courses in order since it will give you a better understanding on how a drug is discovered in the lab before being tested in clinical trials and then launched in the market place.
