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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/diabetes
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课程名称：糖尿病——全球挑战 课程概述：糖尿病和肥胖在富裕和贫穷国家都日益严重。通过本课程，您将了解到最新的糖尿病和肥胖研究，包括生物学、遗传学和临床方面，以及糖尿病和肥胖的预防和流行病学。所有讲座均由全球领先糖尿病研究大学的高水平科学家提供。本课程是EIT健康校园项目的一部分。 课程大纲： 1. **糖尿病的介绍和流行病学** 本模块将聚焦于糖尿病和肥胖的流行病学，并讨论当今您认为最大的糖尿病挑战是什么。 2. **肥胖与糖尿病预防** 探讨身体活动、肥胖、胰岛素抵抗与糖尿病预防之间的关系。 3. **血浆葡萄糖的生理调节** 复杂的葡萄糖调节机制，由Jens Juul Holst教授主讲。 4. **肠促胰素** 学习肠促胰素的生物学，了解其在糖尿病治疗和减重中的应用。 5. **糖尿病的临床表现与治疗** 深入了解糖尿病的临床表现及其治疗，由Allan Vaag教授和Sten Madsbad教授主讲。 6. **糖尿病中的炎症性β细胞破坏** 讨论细胞因子介导的胰腺β细胞破坏，由Thomas Mandrup-Poulsen教授负责。 7. **糖尿病的遗传学方面** 由Torben Hansen教授探讨遗传学在糖尿病理解和治疗中的重要性。 8. **转化医学的相关性** 学习转化医学，并通过案例强调其重要性。 9. **抗糖尿病药物的发展** 探讨潜在药物靶点及如何使用G蛋白偶联受体进行治疗，由Birgitte Holst教授主讲。 10. **基于干细胞的糖尿病治疗** 讨论干细胞治疗糖尿病的优缺点，由Ole Dragsbæk-Madsen教授提出。 11. **运动——它是如何工作的？** 深入了解运动对身体各个器官的影响，由Bente Klarlund教授主讲。 12. **同伴评分作业** 整合所学知识，完成一个同伴评分作业，将所学内容以实践解决方案的形式总结。 希望您能享受我们的课程。 祝好， Jens Juul Holst，Signe Sørensen Torekov 和 Nicolai Wewer Albrechtsen 丹麦哥本哈根大学基础代谢研究中心生物医学科学系
Name:Introduction and epidemiology of diabetes
Description:We are delighted to be able to welcome you to Diabetes – a Global Challenge. In module 1, we will focus on the epidemiology of diabetes and obesity which we lead us to this week discussion topic: "What the greatest diabetes challenges of our time might be in your opinion?" You can either post your opinion as text or as a link to a short video statement.
Name:Obesity and Prevention of Diabetes
Description:We will start module 2 together by discussing physical activity, its influence on obesity, insulin resistance and the prevention of diabetes.
Name:Physiological Regulation of Plasma Glucose
Description:During module 3 we will focus on physiological regulation of plasma glucose. Professor Jens Juul Holst will guide you through the complex regulation of glucose in humans. This will be difficult but hang on you will see the usefulness of what you learn in this module during the subsequent modules where we will discuss the incretins and treatment of hyperglycaemia.
Name:The incretins
Description:Incretin biology is now applied in treating subjects with diabetes and recently approved by the FDA for weight reduction. But what do they do? Don't hesitate to start watching the videos because in this module you will learn all about the incretin lead by Professor Jens Juul Holst.
Name:Clinical manifestation of Diabetes and Treatment
Description:We hope that you enjoyed the previous modules about glucose regulation and incretin biology though they may seem more advanced compared to the first modules. We hope you stay with us and learn more about Clinical Manifestation of Diabetes and Treatment by Professor Allan Vaag and Treatment of Hyperglycemia by Professor Sten Madsbad.
Name:Inflammatory Beta-cell Destruction in Diabetes
Description:Inflammatory beta-cell destruction in diabetes by professor Thomas Mandrup-Poulsen. During this module we Professor Mandrup-Poulsen will guide you through cytokines mediated destruction of the pancreatic beta-cells furthermore their potentiality as drugs targets.
Name:Genetic Aspects of Diabetes
Description:Genetics are important for understanding and treating diabetes. In this module Professor Torben Hansen will discuss the genetic aspects of diabetes
Name:Translational Aspects
Description:Translational medicine? Learn more by watching our new module by Assistant Professor Torekov. In this module we will discuss two cases of translational aspects to highlight its importance. In other words we will go from bench to bedside.
Name:Development of antidiabetic agents
Description:Have you ever thought "how to develop a antidiabetic agent?" Professor Birgitte Holst will take you through some potential drug targets and how to use G-protein coupled receptor for treatment of diabetes.
Name:Stem Cell Based Therapy of Diabetes
Description:Module 10 will focus on 'Stem Cell Based Therapy of Diabetes' and the question 'What are the advantages and disadvantages in cell therapy of diabetes?' is raised by Professor Ole Dragsbæk-Madsen.
Name:Exercise – How Does it Work?
Description:Exercise has many beneficial effects - but how does it actually work? Professor Bente Klarlund will take you through the latest scientific research on how the exercise of skeletal muscles affect our organs and entire body.
Name:Peer Graded Assignment
Description:Try to summarize all what you have learned watching these modules and have fun with writing a peer-graded assignment. The goal is simply to integrate what you have learned and put this together in a practical solution based manner.
Diabetes and obesity are growing health problems in rich and poor countries alike. With this course you will get updated on cutting-edge diabetes and obesity research including biological, genetic and clinical aspects as well as prevention and epidemiology of diabetes and obesity. All lectures are provided by high-profile scientists from one the world's leading universities in diabetes research. This course is part of the EIT Health Campus programme. We hope you will enjoy our course. Best Wishes Jens Juul Holst, Signe Sørensen Torekov and Nicolai Wewer Albrechtsen Department of Biomedical Sciences Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences University of Copenhagen
