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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/clinical-kidney-transplantation
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课程名称：临床肾脏、胰腺及胰岛移植 概述：肾脏移植是现代医学的一项重大进展，为终末期肾病患者提供了高质量的生活。五十多年前，肾脏移植曾是一项实验性、风险高且选择有限的治疗方法，如今在许多国家已成为常规操作。由于终末期肾病患者比例不断增加，预计未来十年肾脏移植数量将急剧上升。 本课程旨在吸引对临床肾脏、胰腺和胰岛移植感兴趣的医学学生和医疗专业人员，适合从事（前）临床移植领域的人员及任何对临床移植研究和知识感兴趣的人士。课程由多学科的移植专业团队授课，提供最新的研究动态。 课程共分为四个模块： 1) 移植前的准备 2) 外科手术及特殊患者情况，包括糖尿病患者 3) 移植后的早期挑战 4) 移植后的晚期挑战 该课程将通过讲座、互动病例、3D视频、与知名专家及患者和捐赠者的访谈以及一款增进知识的严肃游戏等丰富方式进行教学。同时，课程设有一个活跃的论坛，供学员互相交流，成为领域专家，与我们一起学习吧！ 此课程得到欧洲器官移植学会（ESOT）、国际肾脏学会（ISN）及移植学会（TTS）的认可。该MOOC已获得医学继续教育（CME）认证，医疗专业人员可在课程结束后，在'LUMC-Boerhaave CME'获得学分。有关获得CME学分的更多信息，请参阅课程第一周的“获得CME学分的额外介绍”模块。 课程大纲： - 欢迎模块：介绍课程内容，鼓励学员自我介绍并参与讨论。 - 移植前准备模块：探讨移植的必要性及免疫学障碍，利用3D视频辅助理解相关概念。 - 手术与患者模块：关注特殊患者群体及手术程序，提供虚拟现实视频和患者案例讨论。 - 早期挑战模块：分析移植后的早期问题与解决方案，通过3D电影增强理解。 - 晚期挑战模块：讨论移植后的长期结果和主要并发症，强化学员对耐受性概念的认识。 - 期末测验：评估学员对课程的理解和掌握情况。 希望您在这门课程中有所收获，祝您学习愉快！
Name:Welcome to the course
Description:Great that you are joining us! In this course you will learn about clinical kidney, pancreas and islet transplantation and its challenges. Before you start with studying we invite you first go through our introduction module and introduce yourself in the forum to meet your fellow learners. If you encounter any difficulties while studying, please let us know in the forum. For technical difficulties or questions regarding the course certificate, you can always contact the Coursera Learner Helpdesk. Good luck & we hope you enjoy studying in this course!
Name:Before the Transplant
Description:Welcome to this first module of the course! We will answer important questions before transplantation. These include: why is transplantation the preferred option for patients with end stage renal disease? What are the immunological barriers for transplantation? And what are the selection criteria before transplantation? Unique 3D movies about the different immunological tests will help you to understand the concepts. There are also optional lectures, including a fascinating movie about the Eurotransplant allocation system and patient/donor interviews. At the end of the module we will link the contents you have learned to clinical patient cases, patient - donor interviews and a quiz. You can find each other on the discussion forum. With the e-tivities you can apply your knowledge. In the honors lessons more in depth immunological testing and pre transplant screening can be obtained. The lesson also includes peer reviews about important preclinical questions. Have fun and good luck with the first module!
Name:The Procedure and the Patient
Description:Now you know the factors of importance before transplantation, including the immunological barriers and important aspects for patient selection, we can focus on challenged patient groups and on surgical procedures. What does a kidney, pancreas and islet transplantation surgical procedure look like? What is important? And what are the key aspects in elderly patients, patients with diabetes and immunological challenged patients. We have unique visulisations, 360 virtual reality videos and a game about a patient case. Advanced readings will invite you to look at the different subjects in more depth. At the end of the module there are interviews about a patient with diabetes and the transplant recipient and donor to illustrate the impact of life. You can discuss patient cases on the forum together with your peers. In the honors lesson you can apply knowledge about more in depth immunological, surgical and metabolic challenges and living kidney donation. Let’s start and we hope you will enjoy this module.
Name:Early Challenges in Transplantation
Description:You are now familiar with the basic knowledge about challenges in transplant recipients and the surgical transplant procedures. Once the transplantation has been successful, it doesn’t mean everything is stable. What are actually the graft survival data? Which challenges do we face in the first months? How can we tackle these challenges? 3D movies about early surgical challenges and about the targets for immunosuppressives, including cell therapy, will help you to understand the concepts. In addition, we invite you to master the advanced knowledge and to give your opinion in the patient cases in the forum. There is also a serious game about a patient case. Can you solve the challenges? And can you think of a scenario for the game and help us with building? We will make a game of the best scenario, which will be incorporated in the course. In the honors lesson you can learn in more detail about immunological concepts, including the complement system. A patient case will help to show you the importance of this knowledge. Good luck with this module and happy learning!
Name:Late Challenges in Transplantation
Description:Now you’ve learned about the challenges in the early period after transplantation. But what about the late period? What is the long term patient and allograft survival? Have we improved in the last decades? What are the main causes for morbidity and mortality? And can we reach tolerance in the future? We invite you to give your opinion in the patient cases and to discuss it on the forum. There are also advanced readings to look at additional subjects, including recurrence of the kidney disease after transplantation, the organization of dermatological care for the transplant recipient and the role of the patient himself in the whole process. The interview about tolerance gives you insight why pregnancy is of interest to understand the concept of tolerance and which steps have been made from lab research to a clinical protocol. In the honors lesson late challenges will be discussed in more detail, with a focus on infections, recurrence of the kidney disease after transplantation and tolerance. Have fun and good luck with this last module.
Name:Final Quiz
Description:We hope you have enjoyed all the modules. Good luck with the final quiz! If you are interested in an intensive course about transplantation go to the course resources.
Kidney transplantation is a major advance of modern medicine which provides high-quality of life for patients with end-stage renal disease. What used to be an experimental, risky, and very limited treatment option more than 50 years ago is now routinely performed in many countries worldwide. The number of renal transplants is expected to rise sharply in the next decade since the proportion of patients with end stage renal disease is increasing. Are you interested in clinical kidney, pancreas and islet transplantation? If you are a (bio) medical student or a health care professional who works in the (pre) clinical transplant field this might be the course for you. This course is also for anyone interested in the research and knowledge on clinical transplantation. The course will be taught by a multidisciplinary team of transplant professionals and will give you the state of the art updates. It is divided in 4 modules: 1) Before the transplant 2) The surgical procedures and the challenged patient, including the patient with diabetes 3) Early challenges 4) Late challenges after transplantation. The offered modules will include lectures, interactive patient cases, 3D movies, interviews with well-known experts and with patients and a donor, a serious game to increase knowledge of the field and of course an active forum. Become an expert and join us! The course is endorsed by The European Society of Organ Transplantation (ESOT), The International Society of Nephrology (ISN) and The Transplantation Society (TTS). This MOOC has been accredited for Continuing Medical Education (CME). Health care professionals who works in the (pre) clinical transplant field, other health care professionals and general practitioners can obtain CME credit at 'LUMC-Boerhaave CME' upon passing the course. For more information we like to refer to the "Additional introduction for obtaining CME credit" module in week 1 of the course For another interesting course on organ donation and transplantation, see Organ Donation: From Death to Life from Cape Town University https://www.coursera.org/learn/organ-donation
