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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/circadian-clocks
课程评论：没有评论
课程名称：生物钟：如何节律构建生活 概述：本课程面向初学的本科生，具有生物学基础将会有所帮助，但不是绝对必要。课程内容适用于任何生命科学领域的职业追求者，以及那些遭遇生物钟困扰的学习者。 课程大纲： 第一周：介绍“时间生物学”，探讨自然界中观察到的各种节律。主要讲述从细菌到人类的日常或生物节律。 第二周：讨论生物钟如何与24小时的环境进行同步。生物体利用特定的光感受器来实现这一过程，讲解这一过程中典型的特征，例如时差反应。 第三周：深入探讨生物钟生成日常节律和与环境同步的复杂分子机制，并将这些机制与多种生物进行比较。 第四周：解析生物钟如何在一天内协调整体生理和代谢过程，几乎所有的生物过程都是生物钟的调节输出，并讨论这些过程的例子及其调节机制。 第五周：在认识到生物钟的全球控制后，讨论这一时间程序如何从出生到死亡影响我们的生活，以及现代生活中我们如何忽视生物钟。 第六周：最后，探讨生物钟与疾病的关系。讨论逆生物钟生活的后果，生物钟“失灵”时的情况，以及如何利用生物节律系统的知识进行医学诊断和治疗。
Name:WEEK 1
Description:Introduction to 'chronobiology'. What sorts of rhythms are observed in nature? Most of the lecture will be spent on describing daily or circadian rhythms in organisms from bacteria to man.
Name:WEEK 2
Description:Circadian rhythms synchronise to the 24-hour environment. Organisms use specialised photoreceptors to do this and they display characteristic properties in this process. We experience this active synchronisation process for example when we suffer from jet lag!
Name:WEEK 3
Description:We will discuss the elaborate molecular mechanisms that allow circadian clocks to produce their daily rhythms and to synchronise them to its environment. We will compare these mechanisms in a wide range of organisms.
Name:WEEK 4
Description:Circadian clocks serve to orchestrate physiology and metabolism in a coordinated way over the course of the day. Therefore, practically all processes in an organism are regulated outputs of the clock. We'll discuss examples of these processes and ideas about how this circadian regulation works.
Name:WEEK 5
Description:With the appreciation of the clock’s global control, we proceed to discussing how much this temporal programme controls our lives from birth to death and how much we mistreat the circadian clock in modern life.
Name:WEEK 6
Description:Finally, we will look at the clock’s relationship to pathology. What are the consequences of living against the clock, what happens if the clock ‘breaks’, and how can we use our knowledge about the circadian system in medical diagnosis and therapy.
This course is geared towards starting undergraduate students. A solid background in biology will be helpful but not absolutely essential. The material will be of interest to those who are pursuing a career in any of the life sciences as well as anyone who has run up against their biological clock.
