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所在平台: Coursera |
课程主页: https://www.coursera.org/learn/blood-film-morphology
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课程名称：血液涂片形态学 - 实用指南 课程概述：这是一个独特的在线课程，教授学生血液涂片分析的基础知识。该课程特别适合拥有医学科学、医学或病理学背景的学生，适合正在学习或开始在血液学实验室工作的人群，同时也为继续教育提供了宝贵的资源。成功参加此课程虽然希望能进入血液学实验室，但并非必要条件。 课程大纲： 1. 课程介绍：此模块描述血液涂片的背景，概述实验室在分析血液涂片时的流程，包括血常规分析仪的工作原理及其潜在误差来源。还讲解了哪些血常规结果应触发制作血液涂片，以及血涂片的制作方法。 2. 红细胞形态学：该模块围绕红细胞形态学的系统检查方法展开，涵盖红细胞的基本知识、分析微细胞性、巨细胞性和正常细胞性贫血的数量与质量，以及常见变形红细胞的识别与描述。并强调红细胞内的异常情况及其临床意义。 3. 白细胞形态学：此模块集中于白细胞形态学的系统检查，从白细胞数量问题开始，通过独特的结构化过程分析一个异常白细胞群体，涉及反应性白细胞、淋巴增殖性疾病、白血病和骨髓发育不良的形态学分析。 4. 形态学的4P：板块、妊娠、儿科和寄生虫：该模块讨论血液涂片形态学的特定重要领域，包括血小板的定量与定性变化、妊娠期间FBC和涂片的生理及病理变化、儿童血液检查正常范围的不同，以及疟疾的生命周期及其不同种类的形态特点。 5. 现场血液涂片分析 - 整合应用：该模块通过视频展示将之前所学的血液涂片分析方法应用于实际案例，鼓励学员对每个案例进行鉴别诊断，并根据血液涂片的分析结果帮助临床医生做出诊断。 该课程旨在通过系统的学习和案例分析，使学员掌握血液涂片的基本分析技能。
Name:Course Introduction
Description:This 'Course Introduction' Module 1 describes the background to the blood film. It provides you with an overview of what takes place in a laboratory when a film of blood is analyzed. '1.1 - Course Overview' describes the background to the blood film. It explains how a FBC analyser works in '1.2 - The Analyser' and the potential sources of error in analyser results. It then explains which blood counts should trigger the making of a blood film and how that blood film is made in '1.3 - Importance of Making a Blood Film'. The '1.4 - A methodical approach to blood film analysis' lesson ends by suggesting and demonstrating a systematic method for blood film analysis. Module 1 ends with a graded 'End of Module 1 Quiz' for you to complete and a supplementary reading list.
Name:Red Cell Morphology
Description:This 'Red Cell Morphology' module takes you through a systematic method of examination of red cell morphology. It starts with a basic approach in '2.1 Red Cell Morphology Basics', then examines red cell quantity and red cell quality in '2.2 Describing Microcytic, Macrocytic and Normocytic Anaemias in blood films' and '2.3 Recognising and describing common poikilocoytes'. At each step, you are taught a method, provided with the theoretical framework for interpreting abnormalities, and shown examples of abnormalities highlighting their clinical significance in '2.4 Recognising and describing red cell inclusion'. 'The 'Red Cell Morphology' Module ends with a graded 'End of Module 2 Quiz' and a supplementary reading list.
Name:White Cell Morphology
Description:This 'White Cell Morphology' Module 3 takes you through a systematic method of examination of white cell morphology, following the template for blood film analysis in '3.1 A framework for analysing white cell quantitative disorders'. It starts by examining problems of white cell quantity, then examines the many important variants of white cell quality by using a a unique structured process for analysing an abnormal white cell population in '3.2 Analyzing an abnormal leukocyte population'. This takes you through the morphology of reactive white cells, lymphoproliferative diseases, leukaemias and myelodysplasia in '3.3 Analysing lymphoproliferative disorders', '3.4 Analysing acute leukaemias' and '3.5 Examining qualitative changes in white cells' . At each step you are taught a method, provided with the theoretical framework for interpreting abnormalities, and shown examples of abnormalities highlighting their clinical significance. You will be required to complete a grade End of Module 3 quiz and look up the supplementary reading list.
Name:The 4Ps of Morphology - Platelets, Pregnancy, Paediatrics and Parasites
Description:This '4Ps of Morphology - Platelets, Pregnancy, Paediatrics and Parasites' module deals with an assortment of important specific areas of blood film morphology. It first completes the systematic analysis of the blood film by discussing quantitative and qualitative changes in platelets in '4.1 Platelets (Thrombocytopenia & Thrombocytosis)'. In '4.2 Pregnancy', we then discuss the important physiologic and pathologic changes in the FBC and film during pregnancy. The '4.3 Paediatric' lecture emphasises that children are not just little adults by showing how the normal ranges for the FBC and normal appearance of films can differ at different ages, and then discussing a framework for morphologic diagnosis in paediatric anaemia, thrombocytopenia and pancytopenia. The '4.4 Parasite' lesson concludes with a review of malaria – demonstrating the lifecycle of the parasite, the morphologic appearance of different species, and a system to distinguish between different species. You are expected to complete a graded 'End of Module 4' quiz and look up the supplementary reading list.
Name:Live Blood film analysis - Putting it all together
Description:In this 'Live Blood Film Analysis - Putting it all together' module, we demonstrate the use of our method for blood film analysis using videos of real slide examinations for the five cases. The presentation format for each case is similar: each case starts by providing a case history and full blood count (FBC) parameters. You are encouraged to consider a differential diagnosis (DDx) for each case. We will follow the template for blood film analysis. Finally we arrive at a morphologic conclusion and ask you how you can help the clinician reach a diagnosis based on the blood film. The case studies are not assessed. However, viewing them is necessary to see how we apply our method and integrate the concepts taught in Module 1 - 4. As this is a module putting everything you have learned together in individual case studies, there will be no graded 'End of Module 5 quiz' for you to complete
This is a unique online course which teaches students the basics of blood film analysis. This course is specifically tailored to those with a background in Medical Science, Medicine or Pathology who are studying or starting work in a haematology laboratory but also serves as a valuable continuing education resource. To be successful in this course, access to a haematology laboratory is desirable but not essential. This is not a textbook or a laborious examination of every blood film abnormal
