Intermediate Organic Chemistry - Part 1

开始时间: 03/04/2013 持续时间: 8 weeks

所在平台: Coursera

课程类别: 化学

大学或机构: University of Illinois at Urbana-Champaign( 伊利诺伊大学厄巴纳 - 香槟分校)

授课老师: Michael Evans Jeffrey S. Moore Nicholas M. Llewellyn



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This course covers intermediate topics on the structure and reactivity of organic compounds with an emphasis on electronic structure, pericyclic reactions and the chemistry of heteroaromatic compounds. Mechanistic concepts and models of reactivity are developed to build intuition about how organic compounds undergo their chemical transformations. An emphasis will be placed on developing problem-solving skills using frontier molecular orbitals to prepare students to think critically about the organic chemistry of living systems (e.g., nucleic acids, aromatic and heteroaromatic amino acids, etc.). This course and Part 2 are equivalent to a second-semester organic chemistry course, and these courses are especially suited for students in agricultural, nutritional and biological sciences, as well as premedical, predental, and preveterinary programs.


Week 1: Structural Fundamentals; The Curved-arrow Formalism; Introduction to Orbital Theory

Week 2: Constructing & Interpreting Molecular Orbitals; Frontier Molecular Orbital Theory; Non-traditional Resonance

Week 3: π Delocalization & Color; Aromaticity & Cyclic, π-type Molecular Orbitals; Aromatic Heterocycles

Week 4: Cycloaddition Reactions; Cycloaddition Theory; Other Pericyclic Reactions

Week 5: Organic Reaction Mechanisms & Proton Transfer; Strategies for Drawing Mechanisms; Patterns in Electron Flow & Reactivity

Week 6: Reaction Intermediates, Transition States & Stability Trends; Radical Chemistry

Week 7: Photochemical Reactions; Kinetics & Thermodynamics; Catalysis

Week 8: Stereotopic Relationships; Stereochemistry & Symmetry; Facial Stereotopic Relationships





Organic chemistry course covering intermediate topics in structure and reactivity with emphasis on electronic structure, pericyclic reactions and aromatic heterocycles.





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