Introduction to Systematic Reviews and Meta-Analysis

开始时间: 07/13/2015 持续时间: 6 weeks

所在平台: Coursera

课程类别: 其他类别

大学或机构: Johns Hopkins University(约翰•霍普金斯大学)



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We will introduce methods to perform systematic reviews and meta-analysis of clinical trials. We will cover how to formulate an answerable research question, define inclusion and exclusion criteria, search for the evidence, extract data, assess the risk of bias in clinical trials, and perform a meta-analysis. 

Upon successfully completing this course, participants will be able to:

  • Describe the steps in conducting a systematic review
  • Develop an answerable question using the “Participants Interventions Comparisons Outcomes” (PICO) framework
  • Describe the process used to collect and extract data from reports of clinical trials
  • Describe methods to critically assess the risk of bias of clinical trials
  • Describe and interpret the results of meta-analyses


Weeks 1 and 2

  • Introduction to systematic reviews 
  • Framing the question 
Weeks 3 and 4
  • Finding the evidence – searching principles
  • Assessing the risk of bias in clinical trials
  • Meta-bias and qualitative syntheses
Weeks 5 and 6
  • Planning the meta-analysis
  • Introduction to meta-analysis
  • Summary


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Learn to assess data from clinical trials by performing systematic reviews and meta-analyses.