Genomic and Precision Medicine

开始时间: 03/16/2015 持续时间: 7 weeks

所在平台: Coursera

课程类别: 医学

大学或机构: University of California, San Francisco(美国加州大学旧金山分校)

授课老师: Jeanette McCarthy Robert L. Nussbaum

   

课程主页: https://www.coursera.org/course/genomicmedicine

Explore 1600+ online courses from top universities. Join Coursera today to learn data science, programming, business strategy, and more.

课程评论:没有评论

第一个写评论        关注课程

课程详情

Precision medicine has the potential to change fundamentally how health care is practiced, but requires a health care workforce that understands the complexities of this field. One important component of Precision Medicine is the use of an individual’s genomic information to offer targeted treatment, tailored to the individual. Our course aims to provide participants with some baseline knowledge of genomics, an overview of the clinical applications of genomic medicine, the skills to evaluate the clinical validity and utility of new tests, and an appreciation of the associated ethical and social issues inherent in this field

The course is geared toward practicing health care providers, although it should be accessible to anyone with a background in the biological sciences and a basic understanding of genetics.  It is designed to be succinct and clinically-focused, offering both conceptual and practical information about real-world applications of genomics.  The first two lessons offer a basic primer on molecular genomics relevant to the individual patient as well as to patient populations. The remaining five lessons focus on five applications of genomics and present the material as case studies, highlighting the strengths, limitations, and issues that arise in the use of each test.



课程大纲

Week 1: New insights into the structure of the human genome and different types of genetic and non-genetic variation that occur

Week 2: Methods used in patient populations to uncover associations between genome variation and diseases/drug response

Week 3: Predictive tests for common, complex diseases and their role in disease management. Aspects of direct-to-consumer testing are also discussed.

Week 4: Pharmacogenomic testing for drug selection, dosing and predicting adverse effects of commonly prescribed drugs

Week 5: The use of genomics in the reproductive setting: carrier testing, non-invasive prenatal screening, prenatal diagnosis of Mendelian diseases, and newborn screening,

Week 6: The use of next-generation sequencing for solving diagnostic dilemmas

Week 7: Tumor profiling for targeting cancer treatment and the use of blood-based gene expression profiles in cancer prognosis



课程评论(0条)

Deep Learning Specialization on Coursera

课程简介

A critical, unbiased introduction to using new genomic tools for diagnosing and managing disease.

课程标签

0人关注该课程

主题相关的课程