Case-Based Introduction to Biostatistics

开始时间: 05/12/2014 持续时间: 5 weeks

所在平台: Coursera

课程类别: 健康与社会

大学或机构: Johns Hopkins University(约翰•霍普金斯大学)

授课老师: Scott L. Zeger



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The course objective is to enable each student to enhance his or her quantitative scientific reasoning about problems related to human health. Biostatistics is about quantitative approaches - ideas and skills - to address bioscience and health problems. To achieve mastery of biostatistics skills, a student must “see one, do one, teach one.” Therefore, the course is organized to promote regular practice of new ideas and methods.

The course is organized into 3 self-contained two-week modules. Each module except the first is built around an important health problem. The first module reviews the scientific method and the role of experimentation and observation to generate data, or evidence, relevant to selecting among competing hypotheses about the natural world. Bayes theorem is used to quantify the concept of evidence. Then, we will discuss what is meant by the notion of “cause.”
In the second module, we use a national survey dataset to estimate the costs of smoking and smoking-caused disease in American society. The concepts of point and interval estimation are introduced. Students will master the use of confidence intervals to draw inferences about population means and differences of means. They will use stratification and weighted averages to compare subgroups that are otherwise similar in an attempt to estimate the effects of smoking and smoking-caused diseases on medical expenditures.

In the final module, we will study what factors influence child-survival in Nepal using data from the Nepal Nutritional Intervention Study Sarlahi or NNIPPS. Students will estimate and obtain confidence intervals for infant survival rates, relative rates and odds ratios within strata defined by gestational period, singleton vs twin births, and parental characteristics.





Learn to frame and address health-related questions using modern biostatistics ideas and methods.


生物 统计 生物学 统计学 生物统计学 健康 生物统计学入门 生物统计学导论 生物统计学介绍 约翰霍普金斯大学



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