开始时间: 08/24/2015 持续时间: 7 weeks
大学或机构: Duke University(杜克大学)
授课老师： Roger Barr
In this class you will learn how to think about electrically active tissue in terms of individual mechanisms, and you will learn to analyze the mechanisms quantitatively as well as describe them qualitatively. The course uses many of the same examples used by Hodgkin and Huxley, who won the Nobel Prize for their experimental unraveling of the mechanisms of the nerve axon of the giant squid, and their creation of a mathematical model of membranes and propagation to understand its function. That work has been the foundational element of most subsequent understandings of electrically active tissue, whether in nerves, the brain or in muscle, including the heart.
In this course, topics include:
The course will at each step present equations and other quantitative reasoning so that you will be able to go beyond describing what happens qualitatively and be able to link together the phenomena in the mosaic in a quantitative fashion, which is essential to judging whether specific changes in inputs are important to the outcome. Through the use of quantitative analysis, you will learn that all the elements of the system are tied together and be able to link together and analyze the effects of one part on another.
The topics addressed in the course will include:
Nerves, the heart, and the brain are electrical. How do these things work? This course presents fundamental principles, described quantitatively.